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[神经网络在医学中的应用:关于消化不良性病理学]

[Use of neural networks in medicine: concerning dyspeptic pathology].

作者信息

Sáenz Bajo N, Barrios Rueda E, Conde Gómez M, Domínguez Macías I, López Carabaño A, Méndez Díez C

机构信息

Centro de Salud Luis Vives, Area 3 de Atención Primaria, Madrid, Spain.

出版信息

Aten Primaria. 2002 Jun 30;30(2):99-102. doi: 10.1016/S0212-6567(02)78978-6.

DOI:10.1016/S0212-6567(02)78978-6
PMID:12106560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7679651/
Abstract

OBJECTIVES

Development and training of a neurone network that enables the patients who attend the clinic with symptoms of dyspepsia to be classified into two groups: those who very probably have peptic ulcer disease or gastro-oesophageal reflux (GOR) and those more likely to have functional or idiopathic dyspepsia. Results obtained with the neurone network and with other statistical classifiers were compared.

DESIGN

Retrospective study.

SETTING

Three urban primary care clinics. Participants. 81 patients with a diagnosis of dyspepsia, who underwent a digestive tract endoscopy and/ or oesophageal-gastro-duodenal meal, recorded in the clinical notes. Method. Face-to-face interview with a set questionnaire on the symptoms and risk factors of dyspepsia pathology. Data were analysed with determinist classifier, statistical classifier and neurone network based on a multi-layer perception.

RESULTS

The neurone network correctly classified 81% of patients, with negative predictor value of 90% and positive predictor value of 80%.

CONCLUSIONS

The neurone network provides very high accuracy rates in classifying patients on the basis of the presence or otherwise of determined symptoms. There was a tendency to distinguish negative diagnoses (functional or idiopathic dyspepsia) better than positive ones (peptic ulcer disease or GOR). Systematic use of neurone networks in primary care clinics would assist the doctor by increasing the accuracy of diagnostic and/or clinical decisions.

摘要

目的

开发并训练一个神经网络,以便将前来诊所就诊、有消化不良症状的患者分为两组:极有可能患有消化性溃疡疾病或胃食管反流(GOR)的患者,以及更有可能患有功能性或特发性消化不良的患者。比较神经网络与其他统计分类器所获得的结果。

设计

回顾性研究。

地点

三家城市基层医疗诊所。参与者。81名诊断为消化不良的患者,其在临床记录中记录了接受消化道内镜检查和/或食管-胃-十二指肠造影的情况。方法。通过一套关于消化不良病理症状和危险因素的问卷进行面对面访谈。使用基于多层感知器的确定性分类器、统计分类器和神经网络对数据进行分析。

结果

神经网络正确分类了81%的患者,阴性预测值为90%,阳性预测值为80%。

结论

神经网络在根据特定症状的有无对患者进行分类时具有很高的准确率。在区分阴性诊断(功能性或特发性消化不良)方面比阳性诊断(消化性溃疡疾病或GOR)更有优势。在基层医疗诊所系统地使用神经网络将有助于医生提高诊断和/或临床决策的准确性。

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1
[Use of neural networks in medicine: concerning dyspeptic pathology].[神经网络在医学中的应用:关于消化不良性病理学]
Aten Primaria. 2002 Jun 30;30(2):99-102. doi: 10.1016/S0212-6567(02)78978-6.
2
Symptom criteria do not distinguish between functional and organic dyspepsia.症状标准无法区分功能性消化不良和器质性消化不良。
Eur J Surg. 1998 May;164(5):345-52. doi: 10.1080/110241598750004373.
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Role of gastric acid in the aetiology of dyspeptic disease and dyspepsia.胃酸在消化不良性疾病和消化不良病因学中的作用。
Baillieres Clin Gastroenterol. 1998 Sep;12(3):489-502. doi: 10.1016/s0950-3528(98)90020-3.
4
Development and evaluation of a modified Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease to distinguish functional dyspepsia from non-erosive reflux disease.改良的胃食管反流病症状频率量表的制定和评估,以区分功能性消化不良与非糜烂性反流病。
J Gastroenterol Hepatol. 2012 Jul;27(7):1187-91. doi: 10.1111/j.1440-1746.2012.07121.x.
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Accuracy of provisional diagnoses of dyspepsia in patients undergoing first endoscopy.首次接受内镜检查患者消化不良初步诊断的准确性。
Gastrointest Endosc. 2001 Mar;53(3):283-8. doi: 10.1016/s0016-5107(01)70399-9.
6
GPs' ability to diagnose dyspepsia based only on physical examination and patient history.全科医生仅通过体格检查和患者病史来诊断消化不良的能力。
Scand J Prim Health Care. 2000 Jun;18(2):99-104. doi: 10.1080/028134300750018981.
7
[Dyspepsia in general medicine: current diagnostic approach].[普通内科中的消化不良:当前的诊断方法]
Rev Med Brux. 2000 Sep;21(4):A309-13.
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Prevalence, severity and associated features of gastro-oesophageal reflux and dyspepsia: a population-based study.胃食管反流和消化不良的患病率、严重程度及相关特征:一项基于人群的研究。
N Z Med J. 2000 May 26;113(1110):178-81.
9
10
Gastroesophageal reflux disease: prevalence, clinical, endoscopic and histopathological findings in 1,128 consecutive patients referred for endoscopy due to dyspeptic and reflux symptoms.胃食管反流病:1128例因消化不良和反流症状接受内镜检查的连续患者的患病率、临床、内镜及组织病理学表现
Digestion. 2000;61(1):6-13. doi: 10.1159/000007730.

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[Dyspepsia and neuronal networks].[消化不良与神经网络]
Aten Primaria. 2002 Dec;30(10):665; author reply 665-6. doi: 10.1016/s0212-6567(02)79133-6.

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