Skovbjerg Hanne, Sjöström Hans, Norén Ove B
Intern medicinsk klinik, Medicinsk Center, H:S Amager Hospital, DK-2300 København S.
Ugeskr Laeger. 2002 Jun 17;164(25):3329-33.
It is possible that Denmark has a high proportion of patients with undiagnosed coeliac disease in the general population and in such risk groups as patients with autoimmune endocrinological and neurological disorders. An active diagnostic strategy, with screening of patients at risk is proposed. Several gliadin epitopes that might be pathogenetically important are described. Tissue transglutaminase is an autoantigen and a deamidating factor in vitro.
丹麦普通人群以及自身免疫性内分泌和神经疾病患者等风险群体中，可能存在大量未确诊的乳糜泻患者。建议采取积极的诊断策略，对有风险的患者进行筛查。描述了几种可能在发病机制上具有重要意义的麦醇溶蛋白表位。组织转谷氨酰胺酶是一种自身抗原，在体外是一种脱酰胺因子。
