Famularo Giuseppe, Antonelli Salvatore, Barracchini Annalisa, Menichelli Maurizio, Nicotra Giulio Cesare, Minisola Giovanni
Internal Medicine III, San Camillo Hospital, Rome, Italy.
Scand J Rheumatol. 2002;31(2):100-2. doi: 10.1080/03009740252937630.
We report on a patient who had a life-threatening relapse of Behçet's disease associated with a catastrophic antiphospholipid syndrome. The patient experienced over a short time a recurrent acute myocardial infarction, multiple venous thromboses, uveitis, and erythema nodosum. Search for thrombophilic factors was positive only for lupus anticoagulant (LAC) and criteria for the diagnosis of the antiphospholipid antibody syndrome were fulfilled. LAC was not found three months after the discharge. At that time the patient had no evidence of clinically active disease or thrombosis. We suggest that LAC was the main triggering factor for the repeated thromboses in this patient.
我们报告了一名患有危及生命的白塞病复发且伴有灾难性抗磷脂综合征的患者。该患者在短时间内经历了复发性急性心肌梗死、多处静脉血栓形成、葡萄膜炎和结节性红斑。对血栓形成倾向因素的检查仅狼疮抗凝物（LAC）呈阳性，且符合抗磷脂抗体综合征的诊断标准。出院三个月后未检测到LAC。当时患者没有临床活动性疾病或血栓形成的证据。我们认为LAC是该患者反复发生血栓形成的主要触发因素。
