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与系统性红斑狼疮和抗磷脂抗体综合征相关的前房积脓性葡萄膜炎。

Hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome.

作者信息

Zink Jeffrey M, Singh-Parikshak Rita, Johnson C Starck, Zacks David N

机构信息

Retina Service, Kellogg Eye Center, University of Michigan, 1000 Wall St., Ann Arbor, MI 48105, USA.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2005 Apr;243(4):386-8. doi: 10.1007/s00417-004-1022-8. Epub 2004 Oct 13.

DOI:10.1007/s00417-004-1022-8
PMID:15864630
Abstract

PURPOSE

To report a case of hypopyon uveitis associated with systemic lupus erythematosus and antiphospholipid antibody syndrome.

METHODS

Interventional case report: a 49-year-old woman with a history of systemic lupus erythematosus and antiphospholipid antibody syndrome presented with sudden onset of pain, redness, photophobia, and decreased vision in the left eye. Examination revealed hypopyon uveitis and vaso-occlusive retinopathy.

RESULTS

Following treatment with intravenous steroids and cyclophosphamide, the patient's vision improved from CF to 20/80 with no inflammation 6 months following initial presentation.

CONCLUSIONS

In this case, systemic lupus and antiphospholipid syndrome were associated with hypopyon uveitis. Prompt treatment with systemic immunosuppressive therapy resulted in improvement in the hypopyon uveitis and vaso-occlusive retinopathy.

摘要

目的

报告一例与系统性红斑狼疮和抗磷脂抗体综合征相关的前房积脓性葡萄膜炎病例。

方法

介入性病例报告:一名有系统性红斑狼疮和抗磷脂抗体综合征病史的49岁女性,左眼突然出现疼痛、发红、畏光及视力下降。检查发现前房积脓性葡萄膜炎和血管闭塞性视网膜病变。

结果

经静脉注射类固醇和环磷酰胺治疗后,患者视力从眼前指数提高到20/80,初次就诊6个月后无炎症。

结论

在此病例中,系统性红斑狼疮和抗磷脂综合征与前房积脓性葡萄膜炎相关。全身免疫抑制治疗迅速起效,改善了前房积脓性葡萄膜炎和血管闭塞性视网膜病变。

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