Raninen Reino O, Kupari Markku M, Hekali Pauli E
Department of Diagnostic Radiology, Helsinki University Central Hospital, Finland.
Scand J Rheumatol. 2002;31(2):85-8. doi: 10.1080/03009740252937595.
To determine the stiffness of large arteries in patients with Takayasu's arteritis (TA).
A noninvasive ultrasonic method was used to measure Peterson's elastic modulus (Ep), Young's elastic modulus (YM). and the stiffness constant beta of the common carotid arteries in 13 and of the common femoral arteries in 16 patients with TA and in healthy control subjects.
The median carotid artery Ep, YM, and stiffness index beta were statistically significantly higher in patients with TA than in controls (p=0.019, 0.013, and 0.004, respectively). The median femoral artery Ep and YM were also higher in patients with TA than in controls (p=0.005 and 0.039, respectively), and the stiffness constant beta (p=0.127) also tended to be higher in patients with TA relative to healthy persons.
Carotid artery compliance is strongly diminished in patients with TA. A comparable but somewhat less conspicuous change is seen in the femoral arteries.
确定大动脉炎（TA）患者的大动脉僵硬度。
采用无创超声方法测量13例TA患者和16例健康对照者的颈总动脉的彼得森弹性模量（Ep）、杨氏弹性模量（YM）以及僵硬度常数β，同时测量16例TA患者和健康对照者的股总动脉的上述指标。
TA患者颈总动脉Ep、YM和僵硬度指数β的中位数显著高于对照组（p分别为0.019、0.013和0.004）。TA患者股总动脉Ep和YM的中位数也高于对照组（p分别为0.005和0.039），TA患者的僵硬度常数β（p = 0.127）相对于健康人也有升高趋势。
TA患者颈总动脉顺应性显著降低。股动脉也有类似但不太明显的变化。
