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卵巢组织冷冻保存:为未来储存生殖潜能。

Cryopreservation of ovarian tissue: banking reproductive potential for the future.

作者信息

Lee D, Ouhibi N, Battaglia D

机构信息

Division of Reproductive Endocrinology and Infertility, University Fertility Consultants, 1750 SW Harbor Way, Portland, OR 97201-5133, USA.

出版信息

Curr Womens Health Rep. 2001 Oct;1(2):152-6.

Abstract

Cryopreservation of ovarian tissue is a technology that holds promise for banking reproductive potential for the future. It may be apropos for cancer survivors who have undergone treatment with sterility-inducing chemotherapy. Although there is some evidence suggesting cellular and molecular injury with the freezing and thawing process, there are examples in both animals and humans that transplantation of cryopreserved ovarian tissue can effectively bank reproductive potential for the future. This technology may ultimately have applications for in vitro fertilization, and preventing natural or iatrogenic menopause.

摘要

卵巢组织冷冻保存是一项有望为未来储存生殖潜能的技术。对于接受过导致不育的化疗的癌症幸存者而言,这可能是合适的。尽管有一些证据表明冻融过程会造成细胞和分子损伤,但在动物和人类中都有例子显示,移植冷冻保存的卵巢组织能够有效地为未来储存生殖潜能。这项技术最终可能应用于体外受精以及预防自然或医源性绝经。

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