Heineman M J, Beerendonk C C M, Kaandorp C J E
Academisch Medisch Centrum/Universiteit van Amsterdam, afd. Verloskunde en Gynaecologie, Amsterdam.
Ned Tijdschr Geneeskd. 2008 Nov 8;152(45):2452-5.
The treatment of children and young adults with cancer increasingly results in cure, but for a number of female patients this is at the expense of infertility. For women and girls with cancer and the wish to have children in the future, cryopreservation of ovarian tissue may be a solution in the absence of alternatives for the conservation of fertility. Because of the uncertain effectiveness and safety of cryopreservation of ovarian tissue, the Dutch national guideline 'Cryopreservation of ovarian tissue' advises removing and freezing ovarian tissue only if this is done within the framework of scientific research. Reimbursement of this procedure and financing of the relevant and necessary research have not yet been arranged.
儿童和青少年癌症患者的治疗越来越多地带来治愈的希望,但对于许多女性患者来说,这是以不孕为代价的。对于患有癌症且希望未来生育的女性和女孩而言,在缺乏其他生育力保存替代方法的情况下,卵巢组织冷冻保存可能是一种解决方案。由于卵巢组织冷冻保存的有效性和安全性尚不确定,荷兰国家指南《卵巢组织冷冻保存》建议,只有在科学研究框架内进行时,才移除并冷冻卵巢组织。该程序的报销以及相关必要研究的资金尚未安排妥当。