1989 - 2000年苏格兰注射吸毒者中丙型肝炎的流行情况：20世纪90年代末年轻注射吸毒者中的下降趋势停止。
Prevalence of hepatitis C among injectors in Scotland 1989-2000: declining trends among young injectors halt in the late 1990s.
作者信息
Hutchinson S J, McIntyre P G, Molyneaux P, Cameron S, Burns S, Taylor A, Goldberg D J
机构信息
Scottish Centre for Infection and Environmental Health, Glasgow, UK.
出版信息
Epidemiol Infect. 2002 Jun;128(3):473-7. doi: 10.1017/s0950268802006945.
We previously reported a continual decline in anti-HCV prevalence among young injectors from Glasgow and Lothian between 1990 and 1997. The original study was extended to ascertain if the anti-HCV prevalence among injectors from Glasgow, Lothian, Tayside and Grampian had changed since 1997. Residual sera from injectors who had undergone attributable anti-HIV testing were tested anonymously for anti-HCV. In all four regions, no significant changes in prevalence were found among those aged < 25 years during the late 1990s (Glasgow 1997-9/00: 43%-41%; Lothian 1997-9: 13%-17%; Tayside 1997-9: 45%-35%; Grampian 1996-9: 28%-29%). Among those aged > or = 25 years, significant decreases in prevalence were only observed in Glasgow (1997-9/00: 79%-72%, P = 0.03) and Lothian (1997-9: 54%-45%, P = 0.05). The findings highlight that existing harm reduction measures, acknowledged as having helped to reduce the spread of HCV, are not sufficient to bring this epidemic under control and reduce transmission to sporadic levels.
我们之前报告过，1990年至1997年间，格拉斯哥和洛锡安地区年轻注射吸毒者中抗丙型肝炎病毒（anti-HCV）流行率持续下降。最初的研究范围扩大，以确定自1997年以来，格拉斯哥、洛锡安、泰赛德和格兰扁地区注射吸毒者的抗HCV流行率是否发生了变化。对接受过艾滋病病毒（HIV）相关检测的注射吸毒者的留存血清进行了匿名抗HCV检测。在所有四个地区，20世纪90年代末，25岁以下人群的流行率均未发现显著变化（格拉斯哥，1997 - 1999/2000年：43% - 41%；洛锡安，1997 - 1999年：13% - 17%；泰赛德，1997 - 1999年：45% - 35%；格兰扁，1996 - 1999年：28% - 29%）。在25岁及以上人群中，仅在格拉斯哥（1997 - 1999/2000年：79% - 72%，P = 0.03）和洛锡安（1997 - 1999年：54% - 45%，P = 0.05）观察到流行率显著下降。这些发现突出表明，现有的减少伤害措施虽被认为有助于减少HCV传播，但不足以控制这一疫情并将传播降至散发水平。
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