在利多卡因溶液中添加阿芬太尼或阿曲库铵用于静脉区域麻醉的效果。
Effects of adding alfentanil or atracurium to lidocaine solution for intravenous regional anaesthesia.
作者信息
Kurt N, Kurt I, Aygünes B, Oral H, Tulunay M
机构信息
Adnan Menderes University, Department of Anaesthesiology and Reanimation, Faculty of Medicine, Aydin, Turkey.
出版信息
Eur J Anaesthesiol. 2002 Jul;19(7):522-5. doi: 10.1017/s0265021502000856.
BACKGROUND AND OBJECTIVE
The addition of alfentanil or atracurium to lidocaine solution for intravenous regional anaesthesia of the arm may have advantages with respect to improved muscle relaxation and better analgesia. The study investigates these possibilities.
METHODS
We investigated 33 patients. Plain lidocaine solution was administered to Group 1 (n = 11). Alfentanil (0.5 mg) and atracurium (3 mg) were added to the lidocaine solution in Groups 2 (n = 11) and 3 (n = 11), respectively. The onset of sensory and motor block, intra- and postoperative pain scores, and the duration of postoperative analgesia were evaluated.
RESULTS
There was a significant difference in the speed of the onset of sensory block in the hand, but not at the tourniquet site. The onset of the motor block, intra- and postoperative pain scores, and the duration of postoperative analgesia were similar in all groups.
CONCLUSIONS
No clinical benefits of adding alfentanil or atracurium to lidocaine solution for intravenous regional anaesthesia of the arm could be shown.
背景与目的
在用于手臂静脉区域麻醉的利多卡因溶液中添加阿芬太尼或阿曲库铵，在改善肌肉松弛和镇痛方面可能具有优势。本研究对这些可能性进行了调查。
方法
我们对33例患者进行了研究。第1组（n = 11）给予单纯利多卡因溶液。第2组（n = 11）和第3组（n = 11）分别在利多卡因溶液中添加阿芬太尼（0.5 mg）和阿曲库铵（3 mg）。评估感觉和运动阻滞的起效时间、术中和术后疼痛评分以及术后镇痛持续时间。
结果
手部感觉阻滞的起效速度存在显著差异，但在止血带部位无差异。所有组的运动阻滞起效时间、术中和术后疼痛评分以及术后镇痛持续时间相似。
结论
在用于手臂静脉区域麻醉的利多卡因溶液中添加阿芬太尼或阿曲库铵未显示出临床益处。
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