Elhakim M, Sadek R A
Department of Anaesthesia, Faculty of Medicine, Ain-Shams University Cairo, Egypt.
Acta Anaesthesiol Scand. 1994 Aug;38(6):542-4. doi: 10.1111/j.1399-6576.1994.tb03948.x.
This study was undertaken to examine the possible clinical advantages of using muscle relaxant with intravenous regional anaesthesia, (IVRA). Forty unpremedicated adult patients undergoing hand surgery were randomly allocated to receive either 40 ml 0.5% lidocaine or 40 ml 0.5% lidocaine with 2 mg of atracurium. The atracurium group of patients had a significantly greater degree of muscle relaxation, easier reduction of fractures, and better operative conditions (P < 0.01). Less pain was also reported during surgery (P < 0.025), and 5 and 15 min after release of the tourniquet (P < 0.01). Clinically, there was no difference in the speed of onset of block between the two groups. It is concluded that the addition of atracurium to lidocaine improves the operating condition during IVRA with less pain during and after surgery.
本研究旨在探讨在静脉区域麻醉(IVRA)中使用肌肉松弛剂可能存在的临床优势。40例未接受术前用药的成年手部手术患者被随机分为两组,分别接受40毫升0.5%利多卡因或40毫升含2毫克阿曲库铵的0.5%利多卡因。阿曲库铵组患者的肌肉松弛程度明显更高,骨折复位更容易,手术条件更好(P<0.01)。手术期间以及松开止血带后5分钟和15分钟时报告的疼痛也较轻(P<0.025和P<0.01)。临床上,两组之间的阻滞起效速度没有差异。结论是,在利多卡因中添加阿曲库铵可改善IVRA期间的手术条件,减少手术中和手术后的疼痛。