Xue Jie, Guo Zhongwu
Department of Chemistry, Case Western Reserve University, Cleveland OH 44106, USA.
Bioorg Med Chem Lett. 2002 Aug 5;12(15):2015-8. doi: 10.1016/s0960-894x(02)00301-3.
An inner core of the GPI anchor of sperm CD52 antigens was synthesized by a highly convergent process using specially modified inositol, glucosamine and phospholipid as key building blocks. This paper also presents a new and efficient procedure to prepare 1,2,6-differentiated derivatives of inositol for GPI syntheses.