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芬尼氏与海涅克-米库利奇氏幽门成形术用于消化性溃疡行迷走神经切断术患者的长期随机前瞻性比较

Long-term randomized prospective comparison of Finney and Heineke-Mikulicz pylorplasty in patients having vagotomy for peptic ulceration.

作者信息

Thompson B W, Read R C

出版信息

Am J Surg. 1975 Jan;129(1):78-81. doi: 10.1016/0002-9610(75)90171-3.

Abstract

Two hundred patients undergoing vagotomy for duodenal ulceration over a period of forty-three months were randomly given Heineke-Mikulicz or Finney pyloroplasty. One died of a myocardial infarction twenty-four fhours after operation, six-teen died within seven years from conditions unrelated to surgery, nine were lost to follow-up study, and 174 were followed up an average of 5.2 years. These patients were evaluated for signs and symptoms of recurrent ulceration or complications of their operation. A majority underwent postoperative secretoay and gastric emptying studies. The proved rate of ulcer recurrence was higher in patients with Heineke-Mikulicz pyloroplasty (4 per cent versus 2 per cent); however, over-all recurrence (proved, probable, and possible) was 13 per cent in each category. The dumping syndrome, seen in 14.4 per cent with Heineke-Mikulicz and 10.7 per cent with Finney pyloroplasty, was the most common complication...

摘要

在43个月的时间里,200名因十二指肠溃疡接受迷走神经切断术的患者被随机分配接受海涅克-米库利奇幽门成形术或芬尼幽门成形术。1例患者术后24小时死于心肌梗死,16例在7年内死于与手术无关的疾病,9例失访,174例平均随访5.2年。对这些患者进行了复发性溃疡体征和症状或手术并发症的评估。大多数患者接受了术后分泌和胃排空研究。海涅克-米库利奇幽门成形术患者的溃疡复发证实率较高(4%对2%);然而,每类患者的总体复发率(证实、可能和疑似)均为13%。倾倒综合征是最常见的并发症,海涅克-米库利奇幽门成形术患者中发生率为14.4%,芬尼幽门成形术患者中发生率为10.7%……

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