Kastrup W, Lindstedt G, Lundberg P A, Mobacken H
Arch Dermatol Res (1975). 1975 Dec 31;254(3):225-32. doi: 10.1007/BF00557962.
Twenty patients with dermatitis herpetiformis treated with di(4-aminophenyl)-sulphone (Dapsone) were analyzed with respect to serum hemopexin concentration as well as some other haematological parameters. With one exception, there were normal concentrations of serum hemopexin when the haptoglobin and methaemoglobin concentrations were normal. Ten out of 11 patients with haptoglobin below 0.3 g/l, which is the lower limit of reference interval at this laboratory, had their hemopexin concentrations reduced to various extents. There was an inverse relationship between the concentration of serum hemopexin and blood methaemoglobin. There was no correlation between amount of Heinz bodies and the concentrations of blood methaemoglobin, serum haptoglobin or serum hemopexin. It is concluded that serum hemopexin measurement should be of value in the assessment of the severity of the haemolysis caused by the drug treatment in those cases who have a low serum haptoglobin concentration.
对20例接受二（4-氨基苯基）砜（氨苯砜）治疗的疱疹样皮炎患者的血清血红素结合蛋白浓度以及其他一些血液学参数进行了分析。除1例例外，当触珠蛋白和高铁血红蛋白浓度正常时，血清血红素结合蛋白浓度也正常。在本实验室参考区间下限以下（触珠蛋白低于0.3 g/l）的11例患者中，有10例患者的血红素结合蛋白浓度有不同程度降低。血清血红素结合蛋白浓度与血液高铁血红蛋白之间呈负相关。海因茨小体数量与血液高铁血红蛋白、血清触珠蛋白或血清血红素结合蛋白浓度之间无相关性。得出结论，对于血清触珠蛋白浓度较低的患者，血清血红素结合蛋白测定对于评估药物治疗引起的溶血严重程度应有价值。
