In vitro selection and evaluation of RNA aptamers that recognize arginine-rich-motif model peptide on a quartz-crystal microbalance.

作者信息

Fukusho Shinobu, Furusawa Hiroyuki, Okahata Yoshio

机构信息

Department of Biomolecular Engineering, Tokyo Institute of Technology, 4259 Nagatsuda, Midori-ku, Yokohama 226-8501, Japan.

出版信息

Chem Commun (Camb). 2002 Jan 7(1):88-9. doi: 10.1039/b108940b.

DOI:10.1039/b108940b

PMID:12120324

Abstract

To study RNA-peptide interactions, we performed an in vitro selection of RNA on a simple alpha-helical peptide-immobilized quartz-crystal microbalance (QCM) and evaluated the association constants (10(7) M-1) of the selected RNA to the model peptide on the same QCM plate.

摘要