Susaman Nihat, Kaygusuz Irfan
Department of Otolaryngology of Elaziğ SSK Hospital, Elaziğ, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2002 Jan-Feb;9(1):37-40.
We evaluated the efficacy of lidocaine hydrochloride aerosol on postoperative pain relief in patients undergoing tonsillectomy.
The study included 60 patients (25 females, 35 males; mean age 25.43 years; range 16 to 35 years) undergoing tonsillectomy. The procedure was performed by the same surgeons under local anesthesia. The patients were randomly divided into two groups to receive either lidocaine HCl (n = 30) or NaCl (n = 30). A total of 4 mg/kg of 10% lidocaine HCl aerosol and 2 ml of 0.9% NaCl were applied to the tonsillectomy fossa eight times daily, respectively. Evaluation of pain was made on the first, third, and seventh postoperative days using a visual analogue scale.
Significant differences were found between the groups on the first, third, and seventh postoperative days (p < 0.05). In each group, patient's evaluation of pain differed significantly (p < 0.05). The significance levels were higher for lidocaine on the first and third days.
Our results suggest that lidocaine HCl aerosol exerts a therapeutic effect on postoperative pain control in tonsillectomy patients.
我们评估了盐酸利多卡因气雾剂对扁桃体切除术后患者疼痛缓解的疗效。
该研究纳入了60例接受扁桃体切除术的患者(25例女性,35例男性;平均年龄25.43岁;年龄范围16至35岁)。手术由同一位外科医生在局部麻醉下进行。患者被随机分为两组,分别接受盐酸利多卡因(n = 30)或氯化钠(n = 30)。分别每天8次向扁桃体切除窝应用总共4 mg/kg的10%盐酸利多卡因气雾剂和2 ml的0.9%氯化钠。在术后第1天、第3天和第7天使用视觉模拟量表进行疼痛评估。
在术后第1天、第3天和第7天,两组之间存在显著差异(p < 0.05)。在每组中,患者对疼痛的评估有显著差异(p < 0.05)。利多卡因在第1天和第3天的显著性水平更高。
我们的结果表明,盐酸利多卡因气雾剂对扁桃体切除术后患者的疼痛控制具有治疗作用。