纤维蛋白原、血小板第4因子和第XIII因子在人血小板亚细胞组分中的分布。
Distribution of fibrinogen, and platelet factors 4 and XIII in subcellular fractions of human platelets.
作者信息
Broekman M J, Handin R I, Cohen P
出版信息
Br J Haematol. 1975 Sep;31(1):51-5. doi: 10.1111/j.1365-2141.1975.tb00831.x.
Abstract
The distribution of fibrinogen, platelet factor 4 (heparin-neutralizing factor) and factor XIII amongst subcellular fractions of human platelets was determined. It was found that fibrinogen and platelet factor 4 peaked sharply in the region of the density gradient previously shown to be heavily enriched with alpha-granules. By contrast, factor XIII, fibrin-stabilizing factor, was found exclusively in the supernatant.
摘要
测定了纤维蛋白原、血小板第4因子（肝素中和因子）和因子XIII在人血小板亚细胞组分中的分布。结果发现，纤维蛋白原和血小板第4因子在密度梯度区域急剧达到峰值，该区域先前显示富含α颗粒。相比之下，因子XIII（纤维蛋白稳定因子）仅在上清液中被发现。
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