Vlaeyen Johan W S, de Jong Jeroen, Geilen Mario, Heuts Peter H T G, van Breukelen Gerard
Department of Medical, Clinical, and Experimental Psychology, Maastricht University, The Netherlands.
Clin J Pain. 2002 Jul-Aug;18(4):251-61. doi: 10.1097/00002508-200207000-00006.
Several cognitive-behavioral factors contribute to the persistence of pain disability in patients with chronic back pain. Fear-avoidance beliefs and fear of movement/(re)injury in particular have been shown to be strong predictors of physical performance and pain disability. Patients reporting substantial pain-related fear might benefit from exposure in vivo to a set of individually tailored, fear-eliciting, and hierarchically ordered physical movements rather than more general graded activity.
Six consecutive patients with chronic low back pain who reported substantial fear of movement/(re)injury were included in the study. After a no-treatment baseline measurement period, the patients were randomly assigned to one of two interventions. In the first intervention, patients received exposure in vivo first, followed by graded activity. In the second intervention, the sequence of treatment modules was reversed. Before each treatment module, treatment credibility was assessed. Daily measures of pain-related fear, pain catastrophizing, and pain intensity were completed using visual analog scales. In addition, standardized measures of pain disability, pain-related fear, and pain vigilance were taken before and after each treatment module and at the 1-year follow-up. To obtain more objective data on actual activity levels, an ambulatory activity monitor was carried by the patients during 1 week before and after each treatment module.
Time series analysis of the daily measures showed that improvements in pain-related fear and pain catastrophizing occurred only during the exposure in vivo and not during the graded activity, irrespective of the treatment order. Analysis of the pretreatment to post-treatment differences also revealed that decreases in pain-related fear also concurred with decreases in pain disability and pain vigilance and an increase in physical activity levels. All improvements remained at the 1-year follow-up.
多种认知行为因素导致慢性背痛患者的疼痛残疾持续存在。尤其是恐惧回避信念以及对运动/(再)损伤的恐惧,已被证明是身体功能和疼痛残疾的有力预测指标。报告有严重疼痛相关恐惧的患者,可能从体内暴露于一组个性化定制、引发恐惧且按层次排列的身体运动中获益,而非更一般的分级活动。
连续纳入6例报告有严重运动/(再)损伤恐惧的慢性下背痛患者。在无治疗的基线测量期后,患者被随机分配至两种干预措施之一。在第一种干预措施中,患者先接受体内暴露,随后是分级活动。在第二种干预措施中,治疗模块的顺序相反。在每个治疗模块之前,评估治疗可信度。使用视觉模拟量表完成每日疼痛相关恐惧、疼痛灾难化和疼痛强度的测量。此外,在每个治疗模块前后以及1年随访时,进行疼痛残疾、疼痛相关恐惧和疼痛警觉性的标准化测量。为获取关于实际活动水平的更客观数据,患者在每个治疗模块前后各1周佩戴动态活动监测器。
每日测量的时间序列分析表明,无论治疗顺序如何,疼痛相关恐惧和疼痛灾难化的改善仅发生在体内暴露期间,而非分级活动期间。治疗前至治疗后差异的分析还显示,疼痛相关恐惧降低的同时,疼痛残疾和疼痛警觉性也降低,身体活动水平增加。所有改善在1年随访时仍持续存在。