Klaus Alexander, Hinder Ronald A, Swain James, Achem Sami R
Department of Surgery, University Hospital Innsbruck, Austria.
Am Surg. 2002 Jul;68(7):619-23.
Cholelithiasis and gastroesophageal reflux are both very common diseases that may occur simultaneously. Management of asymptomatic gallstones is still controversial. Because severe complications due to gallstones may occur incidental cholecystectomy during nonrelated abdominal surgery may be offered to patients with coexisting gallbladder disease. The aim of this study was to assess the clinical outcome of patients after laparoscopic fundoplication and incidental cholecystectomy for cholelithiasis compared with the outcome of patients after fundoplication alone. We conducted a retrospective chart review and prospective analysis using a questionnaire of the clinical outcome of patients who underwent laparoscopic fundoplication and incidental cholecystectomy from June 1991 to January 2000 in comparison with sex- and age-matched patients who had antireflux surgery alone. Sixty-seven (6.3%) of 1065 patients had a laparoscopic cholecystectomy at the time of laparoscopic antireflux surgery; 101 (75%) of 134 answered the questionnaire. The mean follow-up time was 4.6 years. Laparoscopic cholecystectomy did not influence surgical morbidity or mortality. Postoperative symptom score (1-10) did not show a statistically significant difference regarding bloating, diarrhea, abdominal pain, nausea, vomiting, biliary problems, jaundice, pancreatitis, dysphagia for liquids and solid, heartburn, regurgitation, and chest pain when the two groups were compared. We conclude that incidental cholecystectomy during laparoscopic antireflux surgery is safe and does not appear to influence the clinical outcome of the antireflux procedure.
胆结石和胃食管反流都是非常常见的疾病,且可能同时发生。无症状胆结石的治疗仍存在争议。由于胆结石可能引发严重并发症,对于合并胆囊疾病的患者,在进行非相关腹部手术时可考虑同期行胆囊切除术。本研究的目的是评估与单纯行胃底折叠术的患者相比,腹腔镜胃底折叠术联合同期胆囊切除术治疗胆结石患者的临床结局。我们对1991年6月至2000年1月期间接受腹腔镜胃底折叠术联合同期胆囊切除术的患者的临床结局进行了回顾性病历审查,并使用问卷进行了前瞻性分析,同时与年龄和性别匹配的单纯接受抗反流手术的患者进行比较。1065例患者中有67例(6.3%)在进行腹腔镜抗反流手术时同期行腹腔镜胆囊切除术;134例患者中有101例(75%)回复了问卷。平均随访时间为4.6年。腹腔镜胆囊切除术不影响手术的发病率或死亡率。比较两组患者时,术后症状评分(1 - 10分)在腹胀、腹泻、腹痛、恶心、呕吐、胆道问题、黄疸、胰腺炎、液体和固体吞咽困难、烧心、反流和胸痛方面未显示出统计学上的显著差异。我们得出结论,腹腔镜抗反流手术同期行胆囊切除术是安全的,且似乎不影响抗反流手术的临床结局。