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腹腔镜胆囊切除术后的症状性结局。

Symptomatic outcome after laparoscopic cholecystectomy.

作者信息

Niranjan B, Chumber S, Kriplani A K

机构信息

Department of Surgical Oncology, All India Institute of Medical Sciences (AIIMS), New Delhi, India.

出版信息

Trop Gastroenterol. 2000 Jul-Sep;21(3):144-8.

Abstract

AIMS

Patients with gallstones often present with multiple complaints. We wanted to study the major complaints of our patients undergoing laparoscopic cholecystectomy and the symptomatic relief afforded by the operation.

METHODS

We studied 113 patients with symptomatic gallstone disease who underwent laparoscopic cholecystectomy in a single surgical unit. Patients with proven common bile duct stones, obstructive jaundice, cholangitis, present or past associated abdominal pathology or cholecystoenteric fistula were excluded from the study. The mean follow up period was 18 months (range 10-22 months). A detailed account of the symptoms of gallstones, length of post-operative stay, persistence of symptoms, development of fresh symptoms and resumption of fat containing diet were assessed.

RESULTS

The male to female ratio was 1:4. Common presenting symptoms were abdominal pain (96%), flatulence or feeling of fullness of abdomen (85%), heartburn (66%), belching (62%), sour eructation (52%), vomiting (48%) and nausea (45%). Mean postoperative hospital stay was 28 hours (range 9-68 hours). Biliary pain was relieved in 99% of patients after laparoscopic cholecystectomy (p < 0.001). The non-pain symptoms which are relieved significantly (p < 0.001) included nausea (98%), vomiting (96%) and sour eructation (92%) had better outcome than belching (64%) flatulence (61%) and heart burn (59%). None of the patients developed jaundice after cholecystectomy. Fresh symptoms that developed after laparoscopic cholecystectomy were heart-burn (6%), belching (3.5%), sour eructation (1%) and vomiting (0.5%). Post-cholecystectomy post-prandial diarrhoea occurred in 20% of the patients. The patients' appreciation of a satisfactory cosmetic result of operation scars was 100 percent. Fifteen female patients (13.5%) complained of increased weight gain of more than 5 kg after laparoscopic cholecystectomy [(p > 0.05; not significant (NS)].

CONCLUSION

Laparoscopic cholecystectomy significantly relieved symptoms of gall stone disease. Biliary pain, nausea, vomiting and sour eructations had better outcome compared to belching, flatulence and heartburn, which are also relieved in majority. Postcholecystectomy post-prandial diarrhea was a significant new symptom after cholecystectomy. Pre-operative flatulence and heartburn are risk factors for poor symptom relief. All patients should be pre operatively counselled about the risk of persistence of some non-pain symptoms after laparoscopic cholecystectomy.

摘要

目的

胆结石患者常常有多种不适症状。我们想要研究接受腹腔镜胆囊切除术的患者的主要不适症状以及手术所带来的症状缓解情况。

方法

我们研究了在单一手术科室接受腹腔镜胆囊切除术的113例有症状胆结石疾病患者。经证实有胆总管结石、梗阻性黄疸、胆管炎、当前或既往相关腹部病变或胆囊肠瘘的患者被排除在研究之外。平均随访期为18个月(范围10 - 22个月)。评估了胆结石症状的详细情况、术后住院时间、症状持续情况、新症状的出现以及含脂肪饮食的恢复情况。

结果

男女比例为1:4。常见的主要症状有腹痛(96%)、肠胃气胀或腹部饱胀感(85%)、烧心(66%)、嗳气(62%)、反酸(52%)、呕吐(48%)和恶心(45%)。术后平均住院时间为28小时(范围9 - 68小时)。腹腔镜胆囊切除术后99%的患者胆绞痛得到缓解(p < 0.001)。显著缓解的非疼痛症状(p < 0.001)包括恶心(98%)、呕吐(96%)和反酸(92%),其缓解效果优于嗳气(64%)、肠胃气胀(61%)和烧心(59%)。胆囊切除术后无患者出现黄疸。腹腔镜胆囊切除术后出现的新症状有烧心(6%)、嗳气(3.5%)、反酸(1%)和呕吐(0.5%)。20%的患者出现了胆囊切除术后餐后腹泻。患者对手术疤痕美观效果的满意度为100%。15名女性患者(13.5%)抱怨腹腔镜胆囊切除术后体重增加超过5千克[(p > 0.05;无显著差异(NS)]。

结论

腹腔镜胆囊切除术能显著缓解胆结石疾病的症状。胆绞痛、恶心、呕吐和反酸的缓解效果优于嗳气、肠胃气胀和烧心,后三者大多数也能得到缓解。胆囊切除术后餐后腹泻是胆囊切除术后一个显著的新症状。术前肠胃气胀和烧心是症状缓解不佳的危险因素。所有患者术前都应被告知腹腔镜胆囊切除术后一些非疼痛症状持续存在的风险。

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