Kesek D R, Akerlind L, Karlsson T
Department of Cardiothoracic Anesthesiology, Uppsala University Hospital, Uppsala, Sweden.
Clin Nutr. 2002 Aug;21(4):303-7. doi: 10.1054/clnu.2002.0542.
Early enteral nutrition (EN) improves intestinal integrity, motility and immunocompetence. However, technical problems such as diarrhoea and gastric residual volumes are said to be associated with the method and have prevented its implementation. We have prospectively assessed clinical problems connected to early EN.
Seventy-three consecutive patients eligible for EN were assessed and observed until discharge from the intensive care unit (ICU) or until they resumed oral nutrition. They had surgery for coronary artery bypass grafting and/or valvular disease, thoracic or thoracoabdominal aortic aneurysms or other combined procedures. Two cardiac patients were not subjected to surgery.
In 59/73 patients, EN was started within 3 days. EN was discontinued in half of the patients when they were able to feed themselves. Twelve patients vomited, one of them severely. Dislocation of the nasogastric tube occurred in 28 patients. The 15 patients with diarrhoea were treated with 2-6 broad-spectrum antibiotics during their ICU-stay. Out of 73, 40 patients did not show any gastric residual volume (GRV). GRV decreased during EN in 50% of the patients with fairly large or large residual volumes. The incidence of aspiration pneumonia was 10%.
In the cardiothoracic ICU, individually adjusted early EN is feasible with few problems.
早期肠内营养(EN)可改善肠道完整性、蠕动及免疫功能。然而,腹泻和胃残余量等技术问题被认为与该方法相关,且阻碍了其实施。我们前瞻性地评估了与早期EN相关的临床问题。
对73例符合EN条件的连续患者进行评估并观察,直至其从重症监护病房(ICU)出院或恢复经口营养。他们接受了冠状动脉搭桥术和/或瓣膜疾病、胸主动脉或胸腹主动脉瘤手术或其他联合手术。2例心脏病患者未接受手术。
59/73例患者在3天内开始EN。一半患者在能够自行进食时停止EN。12例患者呕吐,其中1例严重。28例患者发生鼻胃管移位。15例腹泻患者在ICU住院期间接受了2 - 6种广谱抗生素治疗。73例患者中,40例未出现任何胃残余量(GRV)。在GRV较大或很大的患者中,50%在EN期间GRV下降。吸入性肺炎的发生率为10%。
在心胸外科ICU,个体化调整的早期EN可行,问题较少。