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营养支持在成人心脏手术中的作用:国际多学科心脏外科学营养专家组的共识声明。

Role of nutrition support in adult cardiac surgery: a consensus statement from an International Multidisciplinary Expert Group on Nutrition in Cardiac Surgery.

机构信息

Department of Intensive Care Medicine, University Hospital of the RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.

Department of Thoracic, Cardiac and Vascular Surgery, University Hospital, RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.

出版信息

Crit Care. 2017 Jun 5;21(1):131. doi: 10.1186/s13054-017-1690-5.

DOI:10.1186/s13054-017-1690-5
PMID:28583157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5460477/
Abstract

Nutrition support is a necessary therapy for critically ill cardiac surgery patients. However, conclusive evidence for this population, consisting of well-conducted clinical trials is lacking. To clarify optimal strategies to improve outcomes, an international multidisciplinary group of 25 experts from different clinical specialties from Germany, Canada, Greece, USA and Russia discussed potential approaches to identify patients who may benefit from nutrition support, when best to initiate nutrition support, and the potential use of pharmaco-nutrition to modulate the inflammatory response to cardiopulmonary bypass. Despite conspicuous knowledge and evidence gaps, a rational nutritional support therapy is presented to benefit patients undergoing cardiac surgery.

摘要

营养支持是危重心血管手术患者的必要治疗方法。然而,目前缺乏针对这一人群(由精心设计的临床试验组成)的确凿证据。为了明确改善预后的最佳策略,来自德国、加拿大、希腊、美国和俄罗斯的 25 名不同临床专业的国际多学科专家小组讨论了确定可能受益于营养支持的患者的潜在方法、何时最佳开始营养支持以及药物营养在调节体外循环炎症反应中的潜在用途。尽管存在明显的知识和证据差距,但仍提出了合理的营养支持治疗方案,以使接受心脏手术的患者受益。

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本文引用的文献

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Nutrition Therapy in Critically Ill Patients Following Cardiac Surgery: Defining and Improving Practice.心脏手术后危重症患者的营养治疗:定义和改进实践。
JPEN J Parenter Enteral Nutr. 2017 Sep;41(7):1188-1194. doi: 10.1177/0148607116661839. Epub 2016 Aug 1.
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Effect of Sodium Selenite Administration and Procalcitonin-Guided Therapy on Mortality in Patients With Severe Sepsis or Septic Shock: A Randomized Clinical Trial.亚硒酸钠给药和降钙素原指导治疗对严重脓毒症或脓毒性休克患者死亡率的影响:一项随机临床试验。
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Coronary-Artery Bypass Grafting.
冠状动脉搭桥术后:预后营养指数在确定死亡率方面的作用
Anatol J Cardiol. 2025 Apr 21;29(7):331-8. doi: 10.14744/AnatolJCardiol.2025.5109.
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The Malnutrition Universal Screening Tool (MUST) Predicts Postoperative Declines in Activities of Daily Living (ADL) in Patients Undergoing Cardiovascular Open-Heart Surgery.营养不良通用筛查工具(MUST)可预测接受心血管心脏直视手术患者术后日常生活活动能力(ADL)的下降。
Nutrients. 2025 Mar 24;17(7):1120. doi: 10.3390/nu17071120.
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Role of dietitians in optimizing medical nutrition therapy in cardiac surgery patients: A secondary analysis of an international multicenter observational study.营养师在优化心脏手术患者医学营养治疗中的作用:一项国际多中心观察性研究的二次分析
JPEN J Parenter Enteral Nutr. 2025 May;49(4):476-487. doi: 10.1002/jpen.2755. Epub 2025 Apr 6.
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Nutrition, dietary recommendations, and supplements for patients with congenital heart disease.先天性心脏病患者的营养、饮食建议及补充剂
Int J Cardiol Congenit Heart Dis. 2023 Mar 17;12:100449. doi: 10.1016/j.ijcchd.2023.100449. eCollection 2023 Jun.
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Adequacy of oral intakes after cardiac surgery within an ERAS pathway: A prospective observational study.心脏手术后在加速康复外科路径下口服摄入量的充足性:一项前瞻性观察研究。
Nutr Clin Pract. 2025 Jun;40(3):605-615. doi: 10.1002/ncp.11258. Epub 2024 Dec 17.
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Preoperative bioelectrical impedance, measured phase angle, and hand-grip strength as predictors of postoperative outcomes in patients undergoing cardiac surgery: a systematic review.术前生物电阻抗、相位角测量和握力作为心脏手术后患者术后结局的预测因素:系统评价。
BMC Cardiovasc Disord. 2024 Sep 27;24(1):515. doi: 10.1186/s12872-024-04182-6.
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The geriatric nutritional risk index is related to adverse hospitalization outcomes in individuals undergoing cardiac surgery.老年营养风险指数与接受心脏手术的个体的不良住院结局相关。
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J Clin Med. 2024 Jul 9;13(14):4015. doi: 10.3390/jcm13144015.
冠状动脉旁路移植术
N Engl J Med. 2016 May 19;374(20):1954-64. doi: 10.1056/NEJMra1406944.
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Myocardial Ischemia Induces SDF-1α Release in Cardiac Surgery Patients.心肌缺血在心脏手术患者中诱导基质细胞衍生因子-1α释放。
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