Department of Intensive Care Medicine, University Hospital of the RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Department of Thoracic, Cardiac and Vascular Surgery, University Hospital, RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Crit Care. 2017 Jun 5;21(1):131. doi: 10.1186/s13054-017-1690-5.
Nutrition support is a necessary therapy for critically ill cardiac surgery patients. However, conclusive evidence for this population, consisting of well-conducted clinical trials is lacking. To clarify optimal strategies to improve outcomes, an international multidisciplinary group of 25 experts from different clinical specialties from Germany, Canada, Greece, USA and Russia discussed potential approaches to identify patients who may benefit from nutrition support, when best to initiate nutrition support, and the potential use of pharmaco-nutrition to modulate the inflammatory response to cardiopulmonary bypass. Despite conspicuous knowledge and evidence gaps, a rational nutritional support therapy is presented to benefit patients undergoing cardiac surgery.
营养支持是危重心血管手术患者的必要治疗方法。然而,目前缺乏针对这一人群(由精心设计的临床试验组成)的确凿证据。为了明确改善预后的最佳策略,来自德国、加拿大、希腊、美国和俄罗斯的 25 名不同临床专业的国际多学科专家小组讨论了确定可能受益于营养支持的患者的潜在方法、何时最佳开始营养支持以及药物营养在调节体外循环炎症反应中的潜在用途。尽管存在明显的知识和证据差距,但仍提出了合理的营养支持治疗方案,以使接受心脏手术的患者受益。