Akutsu H, Matsumura A, Isobe T, Anno I, Takano S, Itai Y, Nose T
Department of Neurosurgery, Institute of Clinical Medicine, University of Tsukuba, Tennodai 1-1-1,Tsukuba, Ibaraki 305-8575, Japan.
Neuroradiology. 2002 Jul;44(7):574-8. doi: 10.1007/s00234-002-0779-x. Epub 2002 May 3.
We studied chronological magnetic resonance spectral changes in brain abscesses before and after medical and/or surgical treatment. We examined five patients with MRI imaging and (1)H magnetic resonance spectroscopy (MRS) on two or more occasions, using two volume-of-interest patterns, and saw chronological changes related to the evolution of the abscess. A spectrum specific for brain abscess was found in three of the five cases, while two showed a single lactate peak in the first study. In two cases, phenylalanine or alanine appeared in the second study. We observed the disappearance of the specific spectra and a single lactate peak following surgery. Only one patient showed different spectra in different volume of interest.
我们研究了脑脓肿在药物和/或手术治疗前后按时间顺序的磁共振波谱变化。我们对5例患者进行了两次或更多次的MRI成像和氢质子磁共振波谱（MRS）检查，采用两种感兴趣区模式，观察到与脓肿演变相关的按时间顺序的变化。5例中有3例发现了脑脓肿特有的波谱，而另外2例在首次研究中显示为单一乳酸峰。在2例中，第二次研究中出现了苯丙氨酸或丙氨酸。我们观察到手术后特异性波谱和单一乳酸峰消失。只有1例患者在不同的感兴趣区显示出不同的波谱。
