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大剂量东莨菪提取物导致的抗胆碱能中毒。

Anticholinergic poisoning from a large dose of Scopolia extract.

作者信息

Cheng Sheng-Wen, Hu Wei-Hsiung, Hung Dong-Zong, Yang Dar-Yu

机构信息

Department of Emergency Medicine, Taichung Veterans General Hospital, Chung-Sun Medical and Dental College, Taiwan.

出版信息

Vet Hum Toxicol. 2002 Aug;44(4):222-3.

Abstract

Scopolia extract (SE) contains hyoscyamine and scopolamine, which are both anticholinergic. It is usually used as a patent medicine to treat gastrointestinal disorders, to relieve spasmotic discomfort, or to decrease the secretion of gastric acid. Poisoning by SE presents similar symptoms and signs as other types of anticholinergic poisoning. We report a case of severe anticholinergic poisoning after accidentally drinking 8 ml of SE. The patient presented with acute delirium and was successfully treated with physostigmine.

摘要

东莨菪提取物(SE)含有阿托品和东莨菪碱,二者均为抗胆碱能药物。它通常作为成药用于治疗胃肠道疾病、缓解痉挛性不适或减少胃酸分泌。SE中毒的症状和体征与其他类型的抗胆碱能中毒相似。我们报告一例意外饮用8毫升SE后发生严重抗胆碱能中毒的病例。患者出现急性谵妄,经毒扁豆碱治疗成功。

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