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精神分裂症患儿的血液血清素。一项初步研究。

Blood serotonin in schizophrenic children. A preliminary study.

作者信息

Campbell M, Friedman E, Green W H, Collins P J, Small A M, Breuer H

出版信息

Int Pharmacopsychiatry. 1975;10(4):213-21. doi: 10.1159/000468197.

DOI:10.1159/000468197
PMID:1213872
Abstract

Blood serotonin levels were measured in schizophrenic children, all of whom showed manifestations of illness in the first 2 years of life, and controls. Serotonin levels were higher in patients (mean = 0.267 mug/ml) than in controls (mean = 0.218 mug/ml), although the difference did not reach statistical significance. Serotonin levels were significantly higher in patients with florid psychosis and those with lower IQs than in patients in remission or partial remission or higher IQs.

摘要

对患有精神分裂症的儿童及其对照组进行了血液血清素水平的测量。所有精神分裂症儿童在生命的头两年均表现出疾病症状。患者的血清素水平(平均 = 0.267微克/毫升)高于对照组(平均 = 0.218微克/毫升),尽管差异未达到统计学显著性。与处于缓解期或部分缓解期的患者或智商较高的患者相比,患有明显精神病症状的患者和智商较低的患者的血清素水平显著更高。

相似文献

1
Blood serotonin in schizophrenic children. A preliminary study.精神分裂症患儿的血液血清素。一项初步研究。
Int Pharmacopsychiatry. 1975;10(4):213-21. doi: 10.1159/000468197.
2
Platelet size, number, and serotonin content in blood of autistic, childhood schizophrenic, and normal children.
J Autism Dev Disord. 1988 Mar;18(1):119-26. doi: 10.1007/BF02211822.
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Blood serotonin in psychotic and brain damaged children.患有精神疾病和脑损伤儿童的血液血清素水平
J Autism Child Schizophr. 1974 Jan-Mar;4(1):33-41. doi: 10.1007/BF02104998.
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Biological studies in childhood schizophrenia: serotonin uptake by platelets.儿童精神分裂症的生物学研究:血小板对血清素的摄取。
Biol Psychiatry. 1971;3(2):123-8.
5
Abnormalities in platelet 5-hydroxytryptamine efflux in patients with infantile autism.
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Biological studies in childhood schizophrenia: plasma and RBC cholinesterase activity.儿童精神分裂症的生物学研究:血浆和红细胞胆碱酯酶活性
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Psychopathic personality or schizophrenia in aldolescence.
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Serotonin uptake by blood platelets of acute schizophrenic patients.
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Comparison of whole blood serotonin and platelet MAO in children with schizophrenia and major depressive disorder.精神分裂症和重度抑郁症患儿全血5-羟色胺与血小板单胺氧化酶的比较。
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[Changes in surface tension, electric potentials and acetylcholinesterase activity in the blood of children with schizophrenic psychoses treated with neuroleptics].[使用抗精神病药物治疗的精神分裂症患儿血液中表面张力、电势和乙酰胆碱酯酶活性的变化]
Folia Med Cracov. 1984;25(1-2):73-86.

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Association of serotonin concentration to behavior and IQ in autistic children.自闭症儿童血清素浓度与行为及智商的关联。
J Autism Dev Disord. 1987 Mar;17(1):133-40. doi: 10.1007/BF01487265.
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Elevated blood serotonin in autistic probands and their first-degree relatives.自闭症先证者及其一级亲属的血液血清素水平升高。
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