Arkhipova D V, Kornev B M, Popova E N, Osipenko V I, Fokina O A, Privalova E V, Kogan E A, Mukhin N A
Klin Med (Mosk). 2002;80(6):28-33.
Clinical, functional, immunological and x-ray examinations were performed in 32 patients with interstitial pulmonary diseases (14 with idiopathic fibrosing alveolitis, 6 with exogenic allergic alveolitis and 12 with diffuse affection of the connective tissue). The diagnosis was verified using high resolution computed tomography. Lesser circulation was studied with doppler-echocardiography. In 9 patients the diagnosis was verified by thoracoscopic biopsy of the lung. Control group consisted of 16 healthy subjects. The highest pressure in the trunk of the pulmonary artery (31 +/- 4.3 mmHg) was registered in patients with idiopathic fibrosing alveolitis. The severity of pulmonary arterial hypertension correlated with that of respiratory disorders, clinical symptoms and changes in the lungs. Blood pressure in the pulmonary artery trunk tended to elevation with progression of alterations in the lungs registered by computed tomography.
对32例间质性肺疾病患者（14例特发性肺纤维化肺泡炎、6例外源性过敏性肺泡炎和12例结缔组织弥漫性病变）进行了临床、功能、免疫和X线检查。采用高分辨率计算机断层扫描进行诊断验证。用多普勒超声心动图研究肺循环。9例患者经胸腔镜肺活检确诊。对照组由16名健康受试者组成。特发性肺纤维化肺泡炎患者肺动脉主干压力最高（31±4.3 mmHg）。肺动脉高压的严重程度与呼吸障碍、临床症状及肺部变化相关。随着计算机断层扫描显示的肺部病变进展，肺动脉主干血压有升高趋势。
