Neville Brad W, Day Terry A
Department of Stomatology, College of Dental Medicine, Medical University of South Carolina, Charleston, USA.
CA Cancer J Clin. 2002 Jul-Aug;52(4):195-215. doi: 10.3322/canjclin.52.4.195.
In the United States, cancers of the oral cavity and oropharynx represent approximately three percent of all malignancies in men and two percent of all malignancies in women. The American Cancer Society estimates that 28,900 new cases of oral cancer will be diagnosed in 2002, and nearly 7,400 people will die from this disease. Over 90 percent of these tumors are squamous cell carcinomas, which arise from the oral mucosal lining. In spite of the ready accessibility of the oral cavity to direct examination, these malignancies still are often not detected until a late stage, and the survival rate for oral cancer has remained essentially unchanged over the past three decades. The purpose of this article is to review the clinical features of oral cancer and premalignant oral lesions, with an emphasis on early detection.
在美国，口腔癌和口咽癌约占男性所有恶性肿瘤的3%，女性所有恶性肿瘤的2%。美国癌症协会估计，2002年将有28,900例口腔癌新病例被确诊，近7,400人将死于这种疾病。这些肿瘤中超过90%是鳞状细胞癌，起源于口腔黏膜。尽管口腔易于直接检查，但这些恶性肿瘤往往直到晚期才被发现，并且在过去三十年中口腔癌的生存率基本保持不变。本文的目的是回顾口腔癌和癌前口腔病变的临床特征，重点是早期检测。
