Nielsen Jørgen Feldbaek, Nørgaard Pernille
Department of Neurology, Aarhus University Hospital, Nørrebrogade 44, Aarhus, Denmark.
Clin Neurophysiol. 2002 Aug;113(8):1295-300. doi: 10.1016/s1388-2457(02)00153-0.
To study post-exercise facilitation following a non-fatigue exercise in a homogenous group of multiple sclerosis (MS) patients with complaints of muscle fatigue.
In 15 MS patients and matched controls motor evoked potentials (MEP) were recorded from the biceps brachii muscle at time delays of 0.5-30s after an isometric contraction with a torque of 50% of maximal voluntary contraction (MVC) maintained for 2-6s. In addition, MEP was recorded after isometric torque of 25, 50, and 100% of MVC maintained for 6s.
Isometric non-fatigue contraction induced significant post-exercise increase in MEP amplitude in MS patients compared with controls being most pronounced after a contraction for 6s. The post-exercise increase in MEP lasted for longer than 30s in MS patients.
Post-exercise increase of MEP amplitude following a non-fatigue exercise was significant in MS patients with complaints of muscle fatigue compared with healthy subjects.
在一组主诉肌肉疲劳的多发性硬化症（MS）患者同质群体中，研究非疲劳运动后的运动后易化现象。
对15例MS患者及匹配的对照组，在以最大自主收缩（MVC）的50%扭矩进行等长收缩并持续2 - 6秒后，于0.5 - 30秒的时间延迟记录肱二头肌的运动诱发电位（MEP）。此外，在以MVC的25%、50%和100%扭矩进行6秒等长收缩后记录MEP。
与对照组相比，等长非疲劳收缩使MS患者的MEP波幅在运动后显著增加，在收缩6秒后最为明显。MS患者运动后MEP的增加持续超过30秒。
与健康受试者相比，主诉肌肉疲劳的MS患者在非疲劳运动后MEP波幅的运动后增加显著。
