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与非致命性海洛因过量相关的发病率。

Morbidity associated with non-fatal heroin overdose.

作者信息

Warner-Smith Matthew, Darke Shane, Day Carolyn

机构信息

National Drug and Alcohol Research Centre, University of New South Wales, NSW, Australia.

出版信息

Addiction. 2002 Aug;97(8):963-7. doi: 10.1046/j.1360-0443.2002.00132.x.

Abstract

AIMS

To estimate the range and severity of heroin overdose related morbidity.

DESIGN

Cross-sectional survey.

SETTING

Sydney, Australia.

PARTICIPANTS

198 heroin users.

FINDINGS

Sixty-nine per cent had experienced a heroin overdose, 28% in the preceding 12 months. Of those who had overdosed, 79% had experienced at least one overdose-related morbidity symptom. An ambulance had attended overdoses for 59% of subjects, 33% had required hospital treatment for overdose, and 14% had experienced overdose-related complications of sufficient severity to be admitted to a hospital ward. Indirect overdose-related morbidity included: physical injury sustained when falling at overdose (40%), burns (24%) and assault while unconscious (14%). Direct overdose-related morbidity included: peripheral neuropathy (49%), vomiting (33%), temporary paralysis of limbs (26%), chest infections (13%) and seizure (2%).

CONCLUSIONS

There appears to be extensive morbidity associated with non-fatal overdose. This is clearly an area that requires more research to document the prevalence and nature of these harms, and factors associated with them.

摘要

目的

评估海洛因过量相关发病情况的范围和严重程度。

设计

横断面调查。

地点

澳大利亚悉尼。

参与者

198名海洛因使用者。

研究结果

69%的人曾有过海洛因过量经历,其中28%在过去12个月内有过。在那些曾过量用药的人中,79%至少经历过一种与过量用药相关的发病症状。59%的受试者过量用药时曾呼叫过救护车,33%因过量用药需要住院治疗,14%经历过严重程度足以入住医院病房的与过量用药相关的并发症。与过量用药间接相关的发病情况包括:过量用药时摔倒所致身体损伤(40%)、烧伤(24%)以及昏迷时遭袭击(14%)。与过量用药直接相关的发病情况包括:周围神经病变(49%)、呕吐(33%)、肢体暂时麻痹(26%)、胸部感染(13%)和癫痫发作(2%)。

结论

非致命性过量用药似乎会引发广泛的发病情况。显然,这是一个需要更多研究来记录这些危害的发生率、性质及其相关因素的领域。

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