Darke Shane, Ross Joanne, Lynskey Michael, Teesson Maree
National Drug and Alcohol Research Centre, University of New South Wales, NSW 2052, Australia
Drug Alcohol Depend. 2004 Jan 7;73(1):1-10. doi: 10.1016/j.drugalcdep.2003.08.008.
To determine the lifetime and recent histories of attempted suicide among entrants to treatment for heroin dependence in three treatment modalities and a non-treatment comparison group; and to ascertain factors associated with a recent history of attempted suicide.
Cross-sectional structured interview.
Sydney, Australia.
Six hundred and fifteen current heroin users: 201 entering methadone/buprenorphine maintenance (MT), 201 entering detoxification (DTX), 133 entering drug free residential rehabilitation (RR) and 80 not in treatment (NT).
A lifetime history of attempted suicide was reported by 34% of subjects, 13% had attempted suicide in the preceding year and 5% had done so in the preceding month. Females were more likely to have lifetime (44% versus 28%) and 12 month (21% versus 9%) suicide attempt histories. The 12 month prevalence of attempted suicide among treatment groups ranged between 11% (MT, NT) and 17% (RR). Factors associated with recent suicide attempts were: being an RR entrant, female gender, younger age, less education, more extensive polydrug use, benzodiazepine use, recent heroin overdose, Major Depression, current suicidal ideation, Borderline Personality Disorder (BPD)and Post-Traumatic Stress Disorder.
Recent suicidal behaviour is a major clinical problem for heroin users, and for females and RR entrants in particular. An essential adjunct to treatment for heroin dependence is routine screening for depression and suicidal ideation, with the provision of appropriate treatment where needed.
确定三种治疗方式下接受海洛因依赖治疗者及一个非治疗对照组中自杀未遂的终生经历和近期经历;并确定与近期自杀未遂相关的因素。
横断面结构化访谈。
澳大利亚悉尼。
615名当前海洛因使用者:201人进入美沙酮/丁丙诺啡维持治疗(MT),201人进入脱毒治疗(DTX),133人进入无毒品住院康复治疗(RR),80人未接受治疗(NT)。
34%的受试者报告有自杀未遂的终生经历,13%的人在前一年有过自杀未遂,5%的人在前一个月有过自杀未遂。女性更有可能有自杀未遂的终生经历(44%对28%)和12个月内自杀未遂经历(21%对9%)。各治疗组中12个月内自杀未遂的患病率在11%(MT、NT)至17%(RR)之间。与近期自杀未遂相关的因素有:进入RR组、女性、年龄较小、受教育程度较低、多种药物滥用更广泛、使用苯二氮䓬类药物、近期海洛因过量、重度抑郁症、当前有自杀意念、边缘性人格障碍(BPD)和创伤后应激障碍。
近期自杀行为是海洛因使用者尤其是女性和进入RR组者的一个主要临床问题。海洛因依赖治疗的一个重要辅助措施是常规筛查抑郁症和自杀意念,并在需要时提供适当治疗。