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多胞胎数量增加对早产率和低出生体重率的影响:一项国际研究。

The impact of the increasing number of multiple births on the rates of preterm birth and low birthweight: an international study.

作者信息

Blondel Béatrice, Kogan Michael D, Alexander Greg R, Dattani Nirupa, Kramer Michael S, Macfarlane Alison, Wen Shi Wu

机构信息

Epidemiological Research Unit on Perinatal Health and Women's Health, National Institute for Health and Medical Research, Villejuif, France.

出版信息

Am J Public Health. 2002 Aug;92(8):1323-30. doi: 10.2105/ajph.92.8.1323.

Abstract

OBJECTIVES

We studied the effects of twins and triplets on perinatal health indicators in the overall population in the 1980s and 1990s in Canada, England and Wales, France, and the United States.

METHODS

Data were derived mostly from live birth registration. We used rates, relative risks, and population attributable risks for twins and triplets separately.

RESULTS

In each country, the increase in multiple births, and the increase in preterm delivery among multiple births, contributed almost equally to the rise in or stabilization of the overall rates of preterm delivery. Twins contributed a much larger proportion of the preterm deliveries and low-birthweight newborns than did triplets.

CONCLUSIONS

Twins have a major population-based impact on the trends of perinatal health indicators.

摘要

目的

我们研究了20世纪80年代和90年代加拿大、英格兰和威尔士、法国以及美国总体人群中双胞胎和三胞胎对围产期健康指标的影响。

方法

数据主要来源于活产登记。我们分别使用了双胞胎和三胞胎的发生率、相对风险和人群归因风险。

结果

在每个国家,多胞胎出生数量的增加以及多胞胎中早产率的上升,对早产总体发生率的上升或稳定的贡献几乎相同。双胞胎在早产和低体重新生儿中所占比例比三胞胎大得多。

结论

双胞胎对围产期健康指标趋势具有重大的基于人群的影响。

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