Tomecki R
Mater Med Pol. 1975 Oct-Dec;7(4):334-40.
In 36 patients with ulcerative colitis hypersensitivity reactions induced in the colonic mucosa by autologous leukocytes and their extracts were studied. In 77% of cases reactions developed at the site of leukocyte injection and in 69% of cases at the site of leukocyte extra injection. The time of reaction appearance and the character of histological changes suggest that the reactions were of the cell-mediated type. The results of the investigations indicate that cell-mediated reactions may be an important pathogenic factor in ulcerative colitis.
对36例溃疡性结肠炎患者结肠黏膜中由自身白细胞及其提取物诱导的超敏反应进行了研究。在77%的病例中,反应在白细胞注射部位出现,69%的病例在白细胞额外注射部位出现。反应出现的时间和组织学变化特征表明这些反应属于细胞介导型。研究结果表明,细胞介导反应可能是溃疡性结肠炎的一个重要致病因素。