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[局限性前列腺癌:腹腔镜根治性前列腺切除术治疗:841例研究]

[Localized prostatic cancer: treatment with laparoscopic radical prostatectomy: study with 841 cases].

作者信息

Vallancien Guy, Guillonneau Bertrand, Cathelineau Xavier, Baumert Hervé, Doublet Jean-Dominique

机构信息

Institut Mutualiste Montsouris, Département d'urologie, 46 bld Jourdan-75674 Paris.

出版信息

Bull Acad Natl Med. 2002;186(1):117-23; discussion 123-4.

PMID:12146136
Abstract

The authors present their experience in the technique of laparoscopic radical prostatectomy. After 841 operations done from January 1998 to april 2001. They use a trans peritoneal approach with 5 ports of 5 and 10 mm. The prostatectomy is done antegrady and the urethrovesical anastomosis is rebuilt with interrupted 3/0 resorbable sutures. Operating time is 2 hours and 40 minutes (1 h 30 to 6 h 30) Conversion rate is 0.9%, average bleeding is 330 cc and transfusion rate is 2.8%. Bladder catheter is removed between days 3 to 6. hospital stay is 5.8 days. Post-op pain is minimal (2% of antalgics at day 2). There was no death, no embolism, 0.2% of phlebitis, 1.1% of rectal injury. Anstomotic strictures occur in 0.3% of cases. 89.2% of patients are continent after 1 year and 75% of patients under 70 years old who underwent a bilateral nerve sparing procedure were potent at 6 months. Positive margins were observed in 5% of pT2a, 22.5% of pT2b, 22.7% in pT3a and 30% in PT3b. After 2 years 92.5% of patients pT2a and b have a PSA < 0.1 ng/ml. No port seeding or peritoneal invasion by cancer was observed. Laparoscopic radical prostatectomy is a safe surgical procedure which limits the risk of transfusion, of anastomotic stricture, which reduces post op pain and allows a good continence. Potency recovery is promising.

摘要

作者介绍了他们在腹腔镜根治性前列腺切除术技术方面的经验。在1998年1月至2001年4月完成841例手术后,他们采用经腹途径,使用5个5毫米和10毫米的端口。前列腺切除术整块进行,尿道膀胱吻合口用3-0可吸收间断缝线重建。手术时间为2小时40分钟(1小时30分钟至6小时30分钟),中转率为0.9%,平均失血量为330毫升,输血率为2.8%。导尿管在术后第3至6天拔除,住院时间为5.8天。术后疼痛轻微(术后第2天2%使用镇痛药)。无死亡、无栓塞,静脉炎发生率为0.2%,直肠损伤发生率为1.1%。吻合口狭窄发生率为0.3%。89.2%的患者术后1年控尿良好,75%接受双侧神经保留手术的70岁以下患者在术后6个月仍有性功能。pT2a期患者切缘阳性率为5%,pT2b期为22.5%,pT3a期为22.7%,pT3b期为30%。2年后,92.5%的pT2a和b期患者前列腺特异性抗原(PSA)<0.1纳克/毫升。未观察到端口种植或癌性腹膜侵犯。腹腔镜根治性前列腺切除术是一种安全的手术方法,可降低输血风险、吻合口狭窄风险,减轻术后疼痛,并能实现良好的控尿。性功能恢复前景良好。

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[Localized prostatic cancer: treatment with laparoscopic radical prostatectomy: study with 841 cases].[局限性前列腺癌:腹腔镜根治性前列腺切除术治疗:841例研究]
Bull Acad Natl Med. 2002;186(1):117-23; discussion 123-4.
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引用本文的文献

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Surgical margins in radical prostatectomy: a comparison between retropubic and laparoscopic surgery.根治性前列腺切除术中的手术切缘:耻骨后手术与腹腔镜手术的比较
Int Urol Nephrol. 2007;39(3):865-9. doi: 10.1007/s11255-006-9128-z. Epub 2007 Mar 15.