Tangerman A, Bongaerts G, Agbeko R, Semmekrot B, Severijnen R
Department of Gastroenterology and Hepatology, University Medical Center Nijmegen, NL-6500 HB Nijmegen, The Netherlands.
J Clin Pathol. 2002 Aug;55(8):631-3. doi: 10.1136/jcp.55.8.631.
This report investigated the origin of H(2)S in a newborn boy with sulfhaemoglobin induced cyanosis, who died because of multiple organ failure. Frozen material was collected and studied after death. The results suggest that enzymes had been released from deteriorating organs into the blood and abdominal fluid, and that the reaction of one of these enzymes with sulfur containing amino acids might have resulted in increased H(2)S concentrations. It is hypothesised that this release of enzymes resulted from a haemolysin produced by an invasive haemolytic Escherichia coli that was found in the blood and organs of this patient.
本报告调查了一名患有硫血红蛋白诱导性紫绀的新生儿男孩体内硫化氢的来源，该男孩因多器官衰竭死亡。死后收集并研究了冷冻材料。结果表明，酶已从恶化的器官释放到血液和腹腔积液中，其中一种酶与含硫氨基酸的反应可能导致硫化氢浓度升高。据推测，这种酶的释放是由一种侵入性溶血性大肠杆菌产生的溶血素引起的，该细菌在该患者的血液和器官中被发现。
