Steinman A, Banet C, Sutton G A, Yadin H, Hadar S, Brill A
School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.
Vet Rec. 2002 Jul 13;151(2):47-9. doi: 10.1136/vr.151.2.47.
Between August and October 2000, 76 horses were reported by veterinary practitioners as having signs of a neurological disorder, varying from an involvement of the spinal cord alone to the entire central nervous system; 15 of the horses died or were euthanased as a result of their grave prognosis or secondary complications. At the same time, an outbreak of West Nile virus infection affected people and birds, principally domestic geese. West Nile virus was isolated from four of the horses with encephalomyelitis and five other horses seroconverted, indicating that the virus was the probable cause of the outbreak in horses. Three of the cases from which the virus was isolated are described briefly and one case is described in detail. This horse behaved abnormally and had general proprioceptive deficits in all four limbs. Its neurological condition deteriorated after two days and severe inspiratory dyspnoea due to a failure to abduct the arytenoids necessitated a tracheostomy. It died on the fourth day and histological lesions were observed in the brain stem and grey matter of the spinal cord.
2000年8月至10月期间，兽医报告称有76匹马出现神经紊乱症状，症状从仅累及脊髓到整个中枢神经系统不等；其中15匹马因预后严重或出现并发症而死亡或实施了安乐死。与此同时，西尼罗河病毒感染疫情影响了人类和鸟类，主要是家鹅。从4匹患有脑脊髓炎的马身上分离出了西尼罗河病毒，另有5匹马血清转化，表明该病毒可能是此次马匹疫情的病因。简要描述了3例分离出该病毒的病例，并详细描述了1例病例。这匹马行为异常，四肢均有一般性本体感觉缺陷。两天后其神经状况恶化，由于杓状软骨不能外展导致严重吸气性呼吸困难，需要进行气管切开术。它在第四天死亡，在脑干和脊髓灰质中观察到组织学病变。
