来自曼索尼娅盖吉鼓木心材中的香豆素类化合物
Coumarins from the heartwoods of Mansonia gagei Drumm.
作者信息
Tiew Pattara, Puntumchai Apiruk, Kokpol Udom, Chavasiri Warinthorn
机构信息
Natural Products Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
出版信息
Phytochemistry. 2002 Aug;60(8):773-6. doi: 10.1016/s0031-9422(02)00194-2.
Three coumarins and three known mansonones were isolated from the heartwood of Mansonia gagei Drumm. The structures of the three coumarins were elucidated as 3,8-dimethyl-5-isopropyl-6-methoxycoumarin (mansonrin A) 3,8-dimethyl-5-isopropyl-6-hydroxycoumarin (mansorin B) and 2,3-dihydro-3,6,9-trimethyl naphtho[1,8-bc]pyran-7-oxa-8-one (mansorin C) by analyses of physical properties and spectroscopic data. The cytotoxicity of the isolated compounds against brine shrimp Artemia salina Linn. was also evaluated.
从滇南风吹楠（Mansonia gagei Drumm.）的心材中分离出三种香豆素和三种已知的曼宋酮。通过物理性质和光谱数据分析，确定这三种香豆素的结构分别为3,8-二甲基-5-异丙基-6-甲氧基香豆素（曼宋素A）、3,8-二甲基-5-异丙基-6-羟基香豆素（曼宋素B）和2,3-二氢-3,6,9-三甲基萘并[1,8-bc]吡喃-7-氧杂-8-酮（曼宋素C）。还评估了分离出的化合物对卤虫（Artemia salina Linn.）的细胞毒性。
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