Junkers K, Jontofsohn R, Meuret G, Blume K G, Heinze V
Nucl Med (Stuttg). 1975 Dec 15;14(4):355-64.
Radio-iron utilization was nearly normal in these patients, only bilateral nephrectomized patients showed a reduced radio-iron utilization. Red blood half-life span was shortened in all patients, well corresponding to the degree of anemia. Parameters of erythropoesis like plasma iron clearance, bone marrow transit time, erythron iron turnover, non erythron iron turnover and hemolysis iron turnover failed to quantitate disorders of red blood cell regeneration in these patients. No defect in red blood cell enzyme activity could be demonstrated. Enzymes of glycolysis were increased corresponding to the reduced erythrocyte half-life span.
这些患者的放射性铁利用率几乎正常，只有双侧肾切除的患者放射性铁利用率降低。所有患者的红细胞半衰期均缩短，与贫血程度密切相关。红细胞生成参数如血浆铁清除率、骨髓转运时间、红细胞铁周转率、非红细胞铁周转率和溶血铁周转率未能定量这些患者红细胞再生的紊乱情况。未发现红细胞酶活性有缺陷。糖酵解酶相应增加，与红细胞半衰期缩短一致。
