Furuhashi A, Sato E, Nakashima T, Miura Y, Nakayama A, Mori N, Takahashi H, Kobayashi S
Department of Otorhinolaryngology, Nagoya University School of Medicine, Japan.
Undersea Hyperb Med. 2001 Fall;28(4):195-200.
Eight patients with large vestibular aqueduct (LVA) syndrome and acute sensorineural hearing loss that had not responded to intravenous treatment were treated with hyperbaric oxygen(HBO2) therapy. This was performed daily, with 15 treatments per course. Pure tone and speech audiometry were performed on all patients. The mean hearing recovery following HBO2 therapy (20.8 +/- 12.1 dB) was significantly higher than after intravenous treatment (2.3 +/- 7.2 dB) (P < 0.01), although treatment duration was not different between the two therapies. Of the eight patients, five showed complete or partial recovery after one course of HBO2 therapy, and their hearing levels have not since changed. The other three patients showed heating recovery during therapy, but treatment had to be repeated for two or more courses because of progressive or fluctuating hearing loss.We consider HBO2 therapy should be used to treat acute hearing deterioration associated with LVA syndrome if patients do not recover their hearing ability following conventional treatment
8例大前庭导水管（LVA）综合征伴急性感音神经性听力损失且静脉治疗无效的患者接受了高压氧（HBO2）治疗。治疗每日进行，每个疗程15次。对所有患者进行了纯音和言语测听。HBO2治疗后的平均听力恢复（20.8±12.1 dB）显著高于静脉治疗后（2.3±7.2 dB）（P<0.01），尽管两种治疗的疗程持续时间并无差异。8例患者中，5例在一个疗程的HBO2治疗后显示出完全或部分恢复，且此后听力水平未再改变。另外3例患者在治疗期间听力有所恢复，但由于听力进行性下降或波动，治疗不得不重复两个或更多疗程。我们认为，如果患者在常规治疗后听力未恢复，HBO2治疗应用于治疗与LVA综合征相关的急性听力减退。
