Naarding Paul, Leentjens Albert F G, van Kooten Fop, Verhey Frans R J
Department of Psychiatry, University Medical Center Nijmegen, The Netherlands.
J Neuropsychiatry Clin Neurosci. 2002 Summer;14(3):329-34. doi: 10.1176/jnp.14.3.329.
To compare the psychometric properties of the Hamilton Rating Scale for Depression (Ham-D) in patients with stroke, Alzheimer's dementia (AD), and Parkinson's disease (PD), receiver operating characteristic curves were plotted for each group. The concurrent validity of the Ham-D with the DSM-IV criteria for major depressive disorder was high in each of these groups. However, optimal performance of the Ham-D requires the application of disease-specific cutoff scores for screening, diagnostic, and dichotomization purposes. These disease-specific cutoff scores were highest in PD, lower in AD, and lowest in stroke patients.
为比较汉密尔顿抑郁量表（Ham-D）在中风患者、阿尔茨海默病（AD）患者和帕金森病（PD）患者中的心理测量特性，为每组绘制了受试者工作特征曲线。在这些组中的每一组中，Ham-D与DSM-IV重度抑郁症标准的同时效度都很高。然而，Ham-D的最佳性能需要应用针对特定疾病的临界值分数用于筛查、诊断和二分法目的。这些针对特定疾病的临界值分数在PD患者中最高，在AD患者中较低，在中风患者中最低。
