Naess H, Nyland H I, Thomassen L, Aarseth J, Nyland G, Myhr K-M
Department of Neurology, Haukeland Hospital, University of Bergen, Bergen, Norway.
Stroke. 2002 Aug;33(8):2105-8. doi: 10.1161/01.str.0000023888.43488.10.
We sought to determine the incidence and short-term outcome of people aged 15 to 49 years with first-ever cerebral infarction in 1988-1997 in Hordaland County, Norway.
Cases were found from computer search of hospital registries and detailed review of patient records. Stroke subtype was classified according to the major intracranial artery affected. Short-term outcome was evaluated by the modified Rankin Scale (mRS).
A total of 96 women and 136 men met the inclusion criteria. The average annual incidence was 11.4/100 000. Women outnumbered men among those aged <30 years (P=0.059); men predominated among those aged > or =30 years (P=0.004). A total of 148 patients had anterior circulation infarction (64%), and 84 had posterior circulation infarction (36%) (P<0.001). Patients with posterior circulation infarction had better mRS score at discharge (P=0.005). Eighty percent had favorable outcome (mRS score < or =2). The 30-day case fatality rate was 3.4%. The recurrence rate in hospital was 2.2%.
The incidence was in the lower range compared with other reports from western Europe. Although men predominated, there was a strong trend toward more women among patients aged <30 years. Short-term outcome was generally good. Patients with posterior circulation infarction had significantly better short-term outcome.
我们试图确定1988 - 1997年挪威霍达兰郡首次发生脑梗死的15至49岁人群的发病率及短期预后情况。
通过计算机检索医院登记资料并详细查阅患者病历发现病例。根据受影响的主要颅内动脉对卒中亚型进行分类。采用改良Rankin量表（mRS）评估短期预后。
共有96名女性和136名男性符合纳入标准。年平均发病率为11.4/10万。年龄<30岁的人群中女性多于男性（P = 0.059）；年龄≥30岁的人群中男性占主导（P = 0.004）。共有148例患者发生前循环梗死（64%），84例发生后循环梗死（36%）（P<0.001）。后循环梗死患者出院时mRS评分更好（P = 0.005）。80%的患者预后良好（mRS评分≤2）。30天病死率为3.4%。院内复发率为2.2%。
与西欧其他报告相比，该发病率处于较低水平。尽管男性占主导，但年龄<30岁的患者中女性有增多的强烈趋势。短期预后总体良好。后循环梗死患者的短期预后明显更好。
