Department of Nursing, Faculty of Health Sciences, Palacký University Olomouc, Hněvotínská 976/3, 775 15, Olomouc, Czech Republic.
Comprehensive Stroke Center, Department of Neurology, Palacký University Medical School and Hospital, Olomouc, Czech Republic.
Health Qual Life Outcomes. 2023 Jan 19;21(1):4. doi: 10.1186/s12955-023-02090-5.
To synthesize the body of knowledge on the factors influencing the quality of life (QoL) after ischemic stroke (IS) in young adults.
Guidelines regarding the scoping review methodology developed by the Joanna Briggs Institute, and the PRISMA-ScR checklist for a scoping review was used in this paper. A total of 1197 studies were identified through a bibliographic search in Web of Science, MEDLINE, PsycInfo, ScienceDirect, Scopus, and ProQuest Science Database. Articles published between the years 2000-2021 were included.
A total of nine papers were finally selected to respond to the research question. Three studies were prospective longitudinal studies compared QoL between young stroke and age-matched controls from the general population. Across all the analysed studies, 14 variables potentially associated with QoL were identified. QoL in young patients is mainly affected by clinical outcomes after IS (scored by the modified Rankin scale and the Barthel index-favourable initial functional status and higher independence in ADL leads to higher QoL) and psychological factors (post-stroke fatigue and depression-higher levels of fatigue and depression lead to lower QoL). The reviewed studies emphasized the importance of functional outcomes, post-stroke depression, fatigue and anxiety and early return to work.
Further longitudinal studies are needed to identify the trajectory of post-stroke psychosocial symptoms over time and other potential predictors of unfavourable long-term QoL, thus specific young stroke rehabilitation and stroke self-management support programmes should be developed (address physical, psychological factors which influence the psychosocial adaptation post-stroke and the perception of the QoL).
综合影响年轻成年人缺血性脑卒中后生活质量（QoL）的因素的知识体系。
本文使用了乔安娜·布里格斯研究所制定的范围综述方法指南，以及 PRISMA-ScR 范围综述清单。通过在 Web of Science、MEDLINE、PsycInfo、ScienceDirect、Scopus 和 ProQuest 科学数据库中进行文献检索，共确定了 1197 项研究。纳入了 2000 年至 2021 年期间发表的文章。
最终有 9 篇论文被选中回答研究问题。其中 3 项研究是前瞻性纵向研究，比较了年轻脑卒中患者与一般人群中年龄匹配的对照组之间的 QoL。在所有分析的研究中，确定了 14 个可能与 QoL 相关的变量。年轻患者的 QoL 主要受 IS 后的临床结局（用改良 Rankin 量表和巴氏指数评分，初始功能状态良好和 ADL 独立性较高导致 QoL 较高）和心理因素（脑卒中后疲劳和抑郁，疲劳和抑郁程度较高导致 QoL 较低）影响。综述研究强调了功能结局、脑卒中后抑郁、疲劳和焦虑以及尽早恢复工作的重要性。
需要进一步进行纵向研究，以确定脑卒中后心理社会症状随时间的轨迹以及其他可能导致不良长期 QoL 的预测因素，从而应制定特定的年轻脑卒中康复和脑卒中自我管理支持计划（针对影响脑卒中后心理社会适应和 QoL 感知的身体和心理因素）。
