Truniger B
Schweiz Med Wochenschr. 1975 Dec 13;105(50):1677-83.
A few years ago the kidney in chronic renal failure was described as a mass of tissue "without significance, vanishing into the disparity of thousands of fantastically altered organs of strange design and anomalous behaviour". In order to refute this opinion, some of the morphological and pathophysiological evidence is summarized which points to the fact that even in chronic renal failure the remaining nephrons that contribute to renal function behave as a rather homogeneous population characterized by appropriate adaptations of glomerular and tubular functions and by a persistent responsiveness to the changing needs of the patient.
几年前，慢性肾衰竭患者的肾脏被描述为一团“无足轻重的组织，消失在成千上万个结构奇特、行为异常的奇异改变器官的差异之中”。为了反驳这一观点，现将一些形态学和病理生理学证据进行总结，这些证据表明，即使在慢性肾衰竭中，对肾功能有贡献的剩余肾单位表现为相当同质化的群体，其特征是肾小球和肾小管功能的适当适应以及对患者不断变化需求的持续反应性。
