Beduneau G, Cuvelier A, Héliot Ph, Métayer J, Muir J F
Service de Pneumologie, Hôpital de Bois-Guillaume, Rouen, France.
Rev Mal Respir. 2002 Jun;19(3):367-70.
A 25 year old man with no previous history was admitted for a recurrent right sided encysted pleural effusion. Thoracocentesis revealed an exudative lipase-rich-fluid. Because of the persistence of abundant pleural fluid after several thoracocentesis a diagnostic mediastinotomy was performed. This revealed a necrotic cystic mediastinal tumor composed of well differentiated pancreatic tissue, nervous tissue, digestive and respiratory glands, and a dermoid mass with hair and sebacious glands. This led to a diagnosis of benign, mature mediastinal teratoma. We suggest that the chronic pleural effusion was maintained by a fistula from the tumour into the pleural cavity and the secretion of proteolytic enzymes by the well-differentiated pancreatic tissue.
一名既往无病史的25岁男性因复发性右侧包裹性胸腔积液入院。胸腔穿刺抽出富含脂肪酶的渗出液。由于多次胸腔穿刺后仍有大量胸腔积液,遂行诊断性纵隔切开术。结果发现一个坏死性囊性纵隔肿瘤,由分化良好的胰腺组织、神经组织、消化和呼吸腺以及一个含有毛发和皮脂腺的皮样肿块组成。由此诊断为良性成熟纵隔畸胎瘤。我们认为,慢性胸腔积液是由肿瘤与胸腔之间的瘘管以及分化良好的胰腺组织分泌的蛋白水解酶维持的。