Armenean Mircea, Briguet André, Saint-Jalmes Hervé
Département de physique, université Babes-Bolyai, 1, Kogalniceanu, 3400 Cluj-Napoca, Roumanie.
C R Biol. 2002 Apr;325(4):457-63. doi: 10.1016/s1631-0691(02)01449-x.
The extraction of the Nuclear Magnetic Resonance (NMR) spectra of samples having smaller and smaller volumes is a real challenge. Either these reductions of volume are dictated by the difficulties of production of sufficiently large samples or by necessities of miniaturisation of the analysing system, in both cases a careful design of the radiofrequency coil, ensuring an optimum reception of the NMR signal, is required. We have also evaluated the usefulness of electromagnetic simulation software for the design and optimisation of these radio-frequency coils, which are more and more used in biology and health research projects.
提取体积越来越小的样品的核磁共振(NMR)谱是一项真正的挑战。样品体积的减小要么是由于制备足够大的样品存在困难,要么是由于分析系统小型化的需要,在这两种情况下,都需要精心设计射频线圈,以确保最佳接收NMR信号。我们还评估了电磁仿真软件在这些射频线圈设计和优化中的作用,这些线圈在生物学和健康研究项目中越来越常用。