异硒酸盐在生物体内的分布与行为。III. 硒衍生物的辐射防护作用。
Distribution and behaviour of isoselenium salts in organism. III. Radioprotective effect of selenium derivatives.
作者信息
Kozák I, Kronrád L, Dienstbier Z
出版信息
Strahlentherapie. 1975 Nov;150(5):539-45.
PMID:1216256
Abstract
Radioprotective properties of Se-2-aminoethylioselenouronium bromide hydrobromide, 2-aminoselenoazoline and of selenium analogue of mercaptoethylguanidine were followed. Radio-protective effectiveness comparable with classical thiol radioprotectiva was manifested by 2-aminoselenoazoline. In the other two compounds there was on the contrary found a synergism of toxicity and radiation.
摘要
对溴化硒-2-氨基乙基亚硒脲、2-氨基硒唑啉以及巯基乙基胍的硒类似物的辐射防护特性进行了跟踪研究。2-氨基硒唑啉表现出与经典硫醇辐射防护剂相当的辐射防护效果。相反，在另外两种化合物中发现了毒性与辐射的协同作用。
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