Miroshnychenko Z M, Kucherenko M Ie, Tsudzevych B O
Ukr Biokhim Zh. 1975 May-Jun;47(3):374-8.
The content and incorporation intensity of tritium from methionine CH33-groups as well as ATP phosphorus renewal of the skeletal muscles, liver and brain were studied in albino rats as effected by proserin, nicotinic acid and the vagus cutting. It is established that the organs and tissues with a high metabolic activity of ATP are characterized by a higher level of its renewal of ATP. Proserin and the vagus cutting are most likely to affect the renewal of ATP through choline metabolism. Nicotinic acid may affect the renewal of ATP through pyridine nucleotides in the process of oxidative phosphorylation.
研究了在白化大鼠中,毒扁豆碱、烟酸和切断迷走神经对蛋氨酸-CH₃³基团中氚的含量和掺入强度以及骨骼肌、肝脏和大脑中ATP磷更新的影响。已确定,ATP代谢活性高的器官和组织,其ATP更新水平也较高。毒扁豆碱和切断迷走神经很可能通过胆碱代谢影响ATP的更新。烟酸可能在氧化磷酸化过程中通过吡啶核苷酸影响ATP的更新。