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中国上海20岁以上城市居民肥胖及其合并症的流行病学研究。

Epidemiological study on obesity and its comorbidities in urban Chinese older than 20 years of age in Shanghai, China.

作者信息

Jia W P, Xiang K S, Chen L, Lu J X, Wu Y M

机构信息

Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital, China.

出版信息

Obes Rev. 2002 Aug;3(3):157-65. doi: 10.1046/j.1467-789x.2002.00071.x.

Abstract

The aim of this work was to establish the prevalence of overweight and obesity and its associated comorbidities in a Chinese population older than 20 years of age. A group of 2776 randomly selected adults (20-94 years of age) living in the Huayang Community in Shanghai, China, were investigated between 1998 and 2000. Body weight, height, waist and hip circumferences and blood pressure were measured, as were fasting blood glucose, fasting insulin and lipid profile, as well as blood glucose 2 h after a glucose load, and a 75-g glucose tolerance test was performed. The prevalence of overweight was 29.5% and obesity was 4.3%, with a greater number of women being obese than men. More than one-third of the population had abnormal lipid levels. Impaired glucose regulation (IGR) occurred in 10.8%; and 9.8% of the population were classified as having type 2 diabetes mellitus. Hypertension was present in 58.4% of this population. About 21% and 29.3% of the population suffered from high total cholesterol and high triglyceride, respectively. The prevalence of metabolic syndrome was 10.2%. The prevalence of diabetes, IGR and metabolic syndrome increased progressively in association with a body mass index (BMI) of >23 kg m(-2). Hence, although the prevalence of obesity is low in this Chinese population, higher BMI and waist circumference values are clearly associated with an increasing prevalence of comorbidities. The absolute risk of having diabetes, IGR and metabolic syndrome is high in adults with a BMI of > or =23 kg m(-2).

摘要

这项研究的目的是确定中国20岁以上人群中超重和肥胖及其相关合并症的患病率。1998年至2000年间,对居住在中国上海华阳社区的2776名随机选取的成年人(20 - 94岁)进行了调查。测量了体重、身高、腰围和臀围以及血压,还测量了空腹血糖、空腹胰岛素和血脂谱,以及葡萄糖负荷后2小时血糖,并进行了75克葡萄糖耐量试验。超重患病率为29.5%,肥胖患病率为4.3%,肥胖女性人数多于男性。超过三分之一的人群血脂水平异常。糖调节受损(IGR)发生率为10.8%;9.8%的人群被归类为患有2型糖尿病。该人群中高血压患病率为58.4%。分别约21%和29.3%的人群患有高总胆固醇和高甘油三酯。代谢综合征患病率为10.2%。糖尿病、IGR和代谢综合征的患病率随着体重指数(BMI)>23 kg m(-2)而逐渐增加。因此,尽管该中国人群中肥胖患病率较低,但较高的BMI和腰围值显然与合并症患病率增加相关。BMI≥23 kg m(-2)的成年人患糖尿病、IGR和代谢综合征的绝对风险较高。

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