Suppr超能文献

一项横断面研究中,根据高血压状况评估藏族人群代谢成分及其组合的比率和风险因素。

Rate and risk factors of metabolic components and component combinations according to hypertension status in Tibetans in a cross-sectional study.

机构信息

Public Health School, Gansu University of Chinese Medicine, Lanzhou, China.

Department of Environmental Health Sciences, Yale University School of Public Health, New Haven, CT.

出版信息

Medicine (Baltimore). 2022 Oct 28;101(43):e31320. doi: 10.1097/MD.0000000000031320.

Abstract

To estimate the prevalence of metabolic syndrome (MS) and metabolic components and their associated factors and component combinations according to hypertension status in Tibetans living at high altitude. Multistage sampling of 1473 participants (799 hypertensive patients and 674 normotensive subjects). MS prevalence and the number of metabolic components ≥ 3 were significantly higher in the hypertensive than normotensives. In hypertensive patients, the most common component was central obesity and it combined with: high blood pressure, in those with 2 risk factors, plus fasting hyperglycemia, in those with 3 risk factors, and high triglyceride, in those with 4 risk factors. In normotensive subjects, the most common single component was low high-density-lipoprotein cholesterol, and most component combination included central obesity and hyperglycemia in those with 2 risk factors, plus high blood pressure in those with 3 risk factors, and high triglycerides in those with 4 risk factors. Body mass index and female both were associated with increased possibilities of MS in hypertensive and normotensive participants. Low incoming, and high educational levels were associated with an elevated probability of MS in normotensive Tibetans also. The priority of prevention from cardiovascular diseases by targeting metabolic components in the hypertensive was different from normotensives. Different MS components had various lifestyle and socioeconomic factors.

摘要

目的 探讨高原藏族人群中高血压与代谢综合征(MS)及其组分的流行情况,分析其相关因素和组分组合。方法 采用多阶段整群抽样方法,抽取西藏 1473 名常住藏族居民,其中高血压患者 799 例,血压正常者 674 例。结果 高血压组 MS 及≥3 个代谢组分的检出率均高于血压正常组。在高血压患者中,最常见的单一异常为中心性肥胖,其次是 2 个危险因素(高血压+空腹血糖异常)、3 个危险因素(高血压+空腹血糖异常+高三酰甘油血症)和 4 个危险因素(高血压+空腹血糖异常+高三酰甘油血症+低高密度脂蛋白胆固醇血症)。血压正常组中最常见的单一异常为低高密度脂蛋白胆固醇血症,其次是 2 个危险因素(中心性肥胖+空腹血糖异常)、3 个危险因素(中心性肥胖+空腹血糖异常+高血压)和 4 个危险因素(中心性肥胖+空腹血糖异常+高血压+高三酰甘油血症)。在高血压和血压正常人群中,体质指数和女性均与 MS 的发生风险增加有关。在血压正常人群中,低经济收入和较高的文化程度与 MS 发生风险增加有关。结论 高血压患者与血压正常者 MS 及其组分的发生情况存在差异,应根据不同的流行特征进行个体化的防治。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f77c/9622625/0993fbf47de9/medi-101-e31320-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验