Ishizeki Junko, Tomioka Akihiro, Goto Fumio
Department of Anesthesiology and Reanimatology, Gunma University School of Medicine, Maebashi 371-8511.
Masui. 2002 Jul;51(7):780-2.
A 73-year-old male developed intra-operative pulmonary air embolism during cervical tumor resection under general anesthesia. Just after unexpected bleeding (about 700 ml) from the left subclavian vein, PetCO2 decreased suddenly from 32 mmHg to 22 mmHg, SpO2 decreased from 99% to 87% and systolic blood pressure decreased from 110 mmHg to 80 mmHg. Nitrous oxide was discontinued immediately, and blood transfusion and continuous infusion of dopamine (5 micrograms.kg-1.min-1) were started. In spite of the recovery of PetCO2 and blood pressure, hypoxemia (PaO2 54 mmHg at 100% oxygen) continued. The operation was discontinued and the patient was transferred to the intensive care unit. Postoperative chest radiograph showed findings of pulmonary edema. We suspected that the air embolism would have been induced by spontaneous respiration associated with the injury of the subclavian vein. Pulmonary edema may have been induced by pulmonary embolism and volume overload for the acute hemorrhage. The intra-operative pulmonary air embolism can be accelerated by use of nitrous oxide and spontaneous respiration.
一名73岁男性在全身麻醉下进行颈椎肿瘤切除手术时发生术中肺空气栓塞。在左锁骨下静脉意外出血(约700毫升)后,呼气末二氧化碳分压(PetCO2)突然从32毫米汞柱降至22毫米汞柱,血氧饱和度(SpO2)从99%降至87%,收缩压从110毫米汞柱降至80毫米汞柱。氧化亚氮立即停用,并开始输血及持续输注多巴胺(5微克·千克-1·分钟-1)。尽管PetCO2和血压恢复,但低氧血症(吸入100%氧气时动脉血氧分压[PaO2]为54毫米汞柱)仍持续存在。手术停止,患者被转入重症监护病房。术后胸部X线片显示有肺水肿表现。我们怀疑空气栓塞是由锁骨下静脉损伤相关的自主呼吸引起的。肺水肿可能是由肺栓塞和急性出血导致的容量超负荷引起的。使用氧化亚氮和自主呼吸可加速术中肺空气栓塞的发生。