Oonuma M, Hatori M, Hosaka M, Kokubun S
Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan.
Ups J Med Sci. 2001;106(3):211-5. doi: 10.3109/2000-1967-149.
Extraskeletal osteosarcoma is a rare sarcoma that accounts for about 1% of malignant soft tissue tumours. We report an very unusual case of a small-size extraskeletal osteosarcoma arising in the superficial subcutaneous region of the buttock. The patient was a 55 year-old female. She incidentally noticed a small nodule in the right trochanteric region. It was removed under local anesthesia at a private clinic. An additional wide excision was performed at our hospital. There was an 8 mm? 10 mm mass in the subcutaneous tissue. No invasion of the underlying fascia was observed. Microscopic examination of the removed tumour showed bizarre-looking spindle and giant cells with lace-like osteoid. The tumour was diagnosed as extraskeletal osteosarcoma. Chemotherapy with Rosen T-20 was administered to the patient. The patient has survived without recurrence or metastasis for 4 years since the primary surgery. Its superficial location, very small size, wide excision, and chemotherapy were thought to contribute to her long survival.
骨外骨肉瘤是一种罕见的肉瘤,约占恶性软组织肿瘤的1%。我们报告了一例非常不寻常的小尺寸骨外骨肉瘤,发生于臀部浅表皮下区域。患者为一名55岁女性。她偶然发现右转子区有一个小结节。该结节在一家私人诊所局部麻醉下被切除。我们医院又进行了一次广泛切除。皮下组织中有一个8毫米×10毫米的肿块。未观察到肿瘤侵犯深层筋膜。对切除肿瘤的显微镜检查显示有形态怪异的梭形细胞和巨细胞以及花边样骨样组织。该肿瘤被诊断为骨外骨肉瘤。对患者给予了罗森T - 20化疗。自初次手术以来,患者已存活4年,无复发或转移。其浅表位置、非常小的尺寸、广泛切除以及化疗被认为是其长期生存的原因。