Stoimenov K, Stoianova L, Naĭdenov N D, Stefanov S I, Dimitrov D
Vet Med Nauki. 1975;12(4):62-8.
The water-soluble preparation Tylan in conc. 1:2000 in the drinking water for three consecutive days was used successfully against spirochetosis in birds both experimently and in the field practice, as a therapeutic and prophylactic means. 175 (92 per cent) out of 190 affected birds in a spontaneous breakout of spirochetosis recovered. It was found experimentally that Tylan does not interfere with immunogenesis. This made it possible for the authors to vaccinate 10,000 chickens from flocks with manifested spirochetosis along with giving Tylan as a therapeutic and prophylactic agent. Spirochetosis ceased and was no more observed up to the time of slaughter i. e., six months following vaccination. If there are no ticks on the spirochetosis-affected farms it is possible to bring to an end the disease through the therapeutic and prophylactic use of Tylan together with disinfection with 1 per cent sodium hydroxide, no vaccination being needed.
水溶性制剂泰乐菌素(Tylan)以1:2000的浓度连续三天添加到饮用水中,在鸟类螺旋体病的实验和实际防治中均被成功使用。在一次螺旋体病自然爆发中,190只患病禽类中有175只(92%)康复。实验发现泰乐菌素不干扰免疫发生。这使得作者能够对10000只患有螺旋体病的鸡群进行疫苗接种,同时将泰乐菌素作为治疗和预防药物使用。螺旋体病得到控制,直到屠宰时(即接种疫苗六个月后)都未再观察到该病。如果受螺旋体病影响的农场没有蜱虫,通过使用泰乐菌素进行治疗和预防并结合用1%氢氧化钠进行消毒,就有可能终结该病,无需进行疫苗接种。